Series Cast 80

1. 

   Eric McCormack

   Will Truman (24 Episodes)

2. 

   Debra Messing

   Grace Adler (24 Episodes)

3. 

   Sean Hayes

   Jack McFarland (24 Episodes)

4. 

   Megan Mullally

   Karen Walker (24 Episodes)

5. 

   Harry Connick Jr.

   Leo Markus (6 Episodes)

6. 

   Dave Foley

   Stuart Lamarack (5 Episodes)

7. 

   John Cleese

   Lyle Finster (uncredited) (4 Episodes)

8. 

   Blythe Danner

   Marilyn Truman (4 Episodes)

9. 

   Minnie Driver

   Lorraine Finster (3 Episodes)

10. 

    Bobby Cannavale

    Vince D'Angelo (3 Episodes)

11. 

    Leslie Jordan

    Beverley Leslie (3 Episodes)

12. 

    Tim Curry

    Marion Finster (2 Episodes)

13. 

    Laura Kightlinger

    Nurse Sheila (2 Episodes)

14. 

    Eileen Brennan

    Zandra (2 Episodes)

15. 

    Jennifer Lopez

    Jennifer Lopez (2 Episodes)

16. 

    Mira Sorvino

    Diane (1 Episode)

17. 

    James Earl Jones

    Self (1 Episode)

18. 

    Dylan McDermott

    Tom (1 Episode)

19. 

    Stephanie Faracy

    Eva (1 Episode)

20. 

    Bebe Neuwirth

    Bebe Neuwirth (1 Episode)

21. 

    Candice Bergen

    Candice Bergen (1 Episode)

22. 

    Lela Lee

    Ping (1 Episode)

23. 

    Chris Penn

    Rudy (1 Episode)

24. 

    Geena Davis

    Janet Adler (1 Episode)

25. John Edward

    Self (1 Episode)

26. 

    Stacy Galina

    Debbie (1 Episode)

27. 

    Clifford David

    Hotel Manager (1 Episode)

28. 

    Tim Bagley

    Larry (1 Episode)

29. 

    Lea DeLaria

    Nurse Carver (1 Episode)

30. 

    Tom Everett Scott

    Alex (1 Episode)

31. 

    Barry Manilow

    Self (1 Episode)

32. 

    Chloë Sevigny

    Monet (1 Episode)

33. 

    Kathryn Joosten

    Felicia (1 Episode)

34. 

    Amy Farrington

    Phyllis (1 Episode)

35. 

    Michael Angarano

    Elliot (1 Episode)

36. 

    Fiona Hale

    Ruth (1 Episode)

37. 

    Lesley Ann Warren

    Tina (1 Episode)

38. 

    Sharon Osbourne

    Nonny (1 Episode)

39. 

    Emily Rutherfurd

    Joanne (1 Episode)

40. 

    Kali Rocha

    Stephanie (1 Episode)

41. 

    Kenneth Tigar

    John (1 Episode)

42. 

    Tracey Ullman

    Ann (1 Episode)

43. 

    Edie Falco

    Deirdre (1 Episode)

44. 

    Sara Gilbert

    Cheryl (1 Episode)

45. 

    Sara Paxton

    Melanie (1 Episode)

46. 

    Suzanne Pleshette

    Lois Whitley (1 Episode)

47. 

    Debbie Reynolds

    Bobbi Adler (1 Episode)

48. 

    Jerry Levine

    Joe (1 Episode)

49. 

    Peggy Lane

    Woman in Sub Shop (1 Episode)

50. 

    Nathan Anderson

    Andrew (1 Episode)

51. 

    Susan Leslie

    Carol / Woman (1 Episode)

52. 

    Michael Medico

    Josh (1 Episode)

53. 

    Jon Fleming

    Russell (1 Episode)

54. Gordon Davidson

    Self (1 Episode)

55. 

    Alex Boling

    Judge (1 Episode)

56. Bruce Dworkin

    Guy (1 Episode)

57. 

    Mark Cirillo

    Contestant (1 Episode)

58. 

    Christopher Gehrman

    EMT Worker (1 Episode)

59. 

    Gerald Downey

    Clark (1 Episode)

60. 

    Carla Renata

    Receptionist (1 Episode)

61. 

    Kevin Sateri

    Derek (1 Episode)

62. 

    Dion Basco

    Arpie (1 Episode)

63. 

    Karen Bankhead

    Burnadean (1 Episode)

64. 

    Oliver Muirhead

    Maitre D' (1 Episode)

65. 

    Victoria Hoffman

    Waitress (1 Episode)

66. 

    Kelli Kirkland

    Mona (1 Episode)

67. Tim Lucason

    Bartender (1 Episode)

68. Jaimarie Bjorge

    Singing Waitress (uncredited) (1 Episode)

69. 

    Jackie Geary

    Cashier (1 Episode)

70. Gary Riotto

    Waiter (1 Episode)

71. Adrian Mojica

    Security Guard (1 Episode)

72. 

    Matt Champagne

    Don (1 Episode)

73. Ralph Litt

    Judge Holcomb (1 Episode)

74. 

    Donna Ponterotto

    Woman (1 Episode)

75. Adrienne Alitowski

    Woman (1 Episode)

76. Amy Crofoot

    Female Student (1 Episode)

77. Tara O'Connor

    Photographer (1 Episode)

78. Mark Juliano

    Mark Juliano (1 Episode)

79. 

    Jack Black

    Dr. Isaac Hershberg (1 Episode)

80. Don Perry

    Bertram (1 Episode)

Series Crew 32