William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.

  1. Michelle Ashford


Series Cast

  1. Michael Sheen

    Michael Sheen

    Dr. William Masters

    46 Episodes

  2. Lizzy Caplan

    Lizzy Caplan

    Virginia Johnson

    46 Episodes

  3. Caitlin Fitzgerald

    Caitlin Fitzgerald

    Libby Masters

    46 Episodes

  4. Annaleigh Ashford

    Annaleigh Ashford

    Betty DiMello

    34 Episodes

  5. Teddy Sears

    Teddy Sears

    Dr. Austin Langham

    24 Episodes

Full Cast & Crew

Last Season

Masters of Sex

Season 4

2016 | 10 Episodes

The seventies are in full swing and sexual experimentation is all the rage. Masters and Johnson should be celebrating, but their clinic is in legal trouble, their personal lives are in tatters and their relationship is on the rocks.

View All Seasons

Masters of Sex
Masters of Sex



Status Canceled


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  • TV-MA


    This program is specifically designed to be viewed by adults and therefore may be unsuitable for children under 17

Type Scripted

Original Language English

Runtime 60m



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