At Sandover Bridge & Iron Inc., Dean is Dean Smith, the buttoned-down director of Sales & Marketing. Sam is Sam Wesson, a cubicle-dwelling tech support guy. What the heck is going on? Or is it what the Hell?

Familiar plot. Familiar characters. Sam and Dean come across a series of graphic novels called "Supernatural" featuring two demon-hunting brothers named Sam and Dean.

The brothers prepare to fight the forces of the apocalypse in different camps. While Sam and Ruby hunt down Lilith, Dean joins Castiel and Zachariah to take on Lucifer.

Sam, Dean, and Bobby must deal with the aftermath of the Devil's escape from Hell, and receive startling news from the Prophet Chuck.

Dean refuses Sam's efforts to help him battle the Devil, and then wakes up to find himself five years in the future, in a wasteland where Lucifer has begun his endgame by unleashing a virus that transforms humans into zombies.

Ambushed by angry hunters, Sam and Dean are shot and killed and sent to Heaven. Castiel warns Dean that Zachariah is looking for them in Heaven so they need to lay low while searching for an angel named Joshua who can help them since he talks directly to God. While searching for Joshua, the brothers run into some old friends and family members.

Dean begins to think the only way to stop Lucifer is to say yes to Michael, but the angels decide they don't need him anymore. Dean, Sam, and Castiel are horrified at the angels' new game plan and take on Zachariah to prevent an all out war on Earth. Meanwhile, a familiar face returns.

Sam and Dean look to occult lore for a solution to their latest problem, but instead of a resolution, they find much more than either of them had anticipated.