Seven demons, based on the Seven Deadly Sins, are released into the world and the brothers must combat them with the aid of a married Hunter couple.

Sam & Dean track down changelings that are pursuing mothers and their children. A boy they protect bears a strange resemblance to Dean, which at first makes Dean uncomfortable because he once had a one-night stand with the boy's mother Lisa.

The Winchesters are called regarding a robbery of their father's storage unit, and track down the robbers to find the item stolen is a cursed rabbit's foot, which provides great luck until lost, and once lost the previous owner dies within a week.

The brothers investigate the death of a man who committed suicide in a church. However, Sam is forced to team up with an unexpected ally when Dean disappears with a female demon who is interested in him personally.

A young girl trapped in a coma by her wicked stepmother sets off a series of murders based on the fairy tales her father reads her. Meanwhile, Sam tries to get Dean out of his deal.

Bela gets in the way yet again as Sam and Dean are investigating multiple victims who drowned even though they were nowhere near water. Sam and Dean make the creepy discovery that the victims all saw a ghost ship right before dying. They tell Bela to stay away, but she's not so willing to leave, as someone's paying her a lot to solve the same case Sam and Dean are investigating.

The brothers capture a female vampire named Lucy who has no idea how she became one, which leads them to Dixon, a male vampire who is a little too giving. Gordon returns with a vengeance leaving Sam in danger.

In this Christmas-themed episode, Sam and Dean follow the trail of an "anti-Santa" that abducts its victims by using their chimneys. Dean tries to get Sam to celebrate Christmas like they used to but Sam doesn't want to accept that it could be the last one they'll spend together.

The seemingly harmless practices of a group of neighborhood witches goes bad when one of them kills a woman. Ruby offers her assistance... but she has a few secrets of her own.

Dean interrogates a college student after the death of Dr. Greggs. Bobby, Sam and Dean all discover the truth behind the fatal death when they all get locked in a nightmare of their own.

Dean is killed after looking into a case about the disappearance of a man with Sam. The next morning, Sam is shocked to find Dean alive and is hit with the realization that he is reliving the day before.

FBI Agent Henricksen finally captures Sam and Dean, but is caught in the middle when a horde of demons descends on the small-town jail to eliminate the brothers.

In a change of pace, Sam and Dean decide to star in a violent, profane reality show named Ghostfacers. The show takes them to the haunted Morton Mansion, and they soon realize they're in over their heads.

Sam and Dean search for a Crocotta that uses the phone and computer as a means to communicate with people. Its goal is to get people to commit suicide and take their soul. Dean gets some news from an unlikely source about a demon holding the contract to his soul.

Sam and Dean discover a doctor who, back in 1816, became obsessed with finding the secret of eternal life by taking people's vital organs. Meanwhile, Bobby finds Bela and Dean leaves Sam to confront her.

Sam, Dean, and Bobby hunt down Lilith and fight her and her demons in a final effort to save Dean's life.

Dean wakes up in his own coffin. How did he return from the dead? What caused the hand-shaped welt on his shoulder? And what happened in the four months he spent in Hell, time he can't remember?

After Dean's encounter with Castiel, Dean, Sam and Bobby brush up on their biblical lore when they're attacked by the vengeful spirits of people from the Winchesters' past. They're warned it's a sign that someone is trying to break seals which will bring on the apocalypse.

Back to the future, Castiel sends Dean to 1973 Lawrence, Kansas, where he meets a nice young couple named John and Mary Winchester. Dean's parents. And Mary has a secret.

Dark powers. Dean fears Sam is using his paranormal gifts in conflict with God's plan. And an ordinary guy in an ordinary town gets a major case of the munchies. It starts with steak - and moves to human flesh.

In a black-and-white world reminiscent of classic horror flicks, the brothers tangle with a vampire, a werewolf and a mummy who are thinning the crowds at a quaint Oktoberfest.

Hell beckons again when Dean is stricken with a mysterious illness that frightens its sufferers to death. Sam and Dean scramble to find the cause of the disease in time to save Dean from sure death.

Chomping candy, bobbing for apples. Halloween is such fun. Until gruesome deaths signify another seal is being broken. To stop it, Castiel and another angel plan a mass annihilation of the town.

Want to score a hot girlfriend, win the lottery or have your favorite teddy bear come to life? Then plunk a coin in a small town's wishing well and stand back. One problem: The wishes come true with a twist.

What happened to Sam during the months Dean was dead? During the search for a girl named Anna Milton, who has a mysterious connection to angels, Sam reveals the astonishing events of the summer.

"I'll Kill her gentle." The angels want Anna dead, so Sam and Dean go on the run with the frightened girl, determined to discover the secret that has set the furies of Heaven on her.

Dad, Mom, two kids and a dog. An all-American family doesn't stand a ghost of a chance against the bloodthirsty force that turns their new home-sweet-home into a haunted house.

Aging magician The Incredible Jay performs the dangerous Table of Death trick and emerges unscathed. Jay cheated the Grim Reaper, but one of his rivals didn't. He checked out while Jay was doing his act.

Fast times at Truman High. Murder brings Sam and Dean back to one of their old high schools, where they investigate possible demonic possession and take a few trips down memory lane.

In a small town in Iowa, three loving husbands kill their wives. Turns out these guys believe in spreading their love around: Each is spending plenty of the family income on strippers at a nearby nudie bar.

Reapers take a break from work, and that means no one can die. But the escorts to the next world aren't off getting some R&R, unless you call being held hostage by a demon restful and relaxing.

Can torture be God's work? After seven angels are mysteriously murdered, Castiel and Uriel demand that Dean use the agony-inducing skills he learned in Hell to extract information from Alastair.

At Sandover Bridge & Iron Inc., Dean is Dean Smith, the buttoned-down director of Sales & Marketing. Sam is Sam Wesson, a cubicle-dwelling tech support guy. What the heck is going on? Or is it what the Hell?

Familiar plot. Familiar characters. Sam and Dean come across a series of graphic novels called "Supernatural" featuring two demon-hunting brothers named Sam and Dean.

Meet the Winchester boys: Dean, Sam and... Adam. The Winchesters discover they have a younger half-brother, whose mother vanishes just as a long-dormant grave robber renews his ghoulish career.

The body Castiel walks around in isn't his. Instead, it belongs to a regular guy named Jimmy who wants his body - and his life - back. He gets the body. But the life may be a different story.

Dean and Bobby have something frightening locked in Bobby's panic room: Sam, contaminated by demon blood. But as the apocalypse draws nearer, Bobby wants to free Sam to battle on their side.

The brothers prepare to fight the forces of the apocalypse in different camps. While Sam and Ruby hunt down Lilith, Dean joins Castiel and Zachariah to take on Lucifer.