In the eleventh season opener, Amy gives Sheldon an answer to his proposal while Howard and Bernadette struggle with some unexpected news.

Leonard angers the university – and the entire physics community – after he gives an embarrassing interview. Also, Amy and Bernadette bond over having to hide their success from Sheldon and Howard.

Sheldon struggles with picking a wedding date. Amy decides she wants a wedding near a cliff which Sheldon doesn't want. Meanwhile Raj and Stuart fight over one of Bernadette's co-workers.

Sheldon and Koothrappali confide in Bernadette when they can't handle Amy and Wolowitz working together. Also, Penny and Leonard learn new tactics for how to deal Sheldon from an unlikely source.

Sheldon goes head-to-head with Wil Wheaton for the role of the new Professor Proton. Also, Penny steps in to take care of Halley when Bernadette and Wolowitz both wind up on bed rest.

Sheldon and Bert collaborate on a research project, despite Sheldon’s embarrassment. Also, Penny and Bernadette coach Koothrappali on how to navigate his relationship with Ruchi.

Leonard and Wolowitz are furious after they learn Sheldon went to work with the military behind their backs. Also, while Bernadette is on bed rest, she asks Raj to do some digging when she suspects Ruchi is trying to steal her job.

Sheldon tries to teach the guys a lesson after they cut him out of a potentially valuable Bitcoin investment. Also, a seven-year-old video reveals a secret about Leonard and Penny's relationship.

Sheldon and Amy try to eliminate stress from wedding planning by applying math to the process. Also, Koothrappali “breaks up” with Wolowitz after realizing his best friend is actually hurting his confidence.

Sheldon and Wolowitz plan birthday celebrations for Amy and Halley, respectively. Also, Leonard get a Christmas letter from his brother that causes him to spiral out about his own lack of accomplishments.

Sheldon and Amy will try to use science to see who should be their Maid of Honor and Best Man.

When Sheldon kicks Amy out to work solo, she and Leonard bond during a series of science experiments. Also, Bert the geologist replaces Wolowitz in the band Footprints on the Moon, and Sheldon finds Penny a surprising source of scientific inspiration.

Koothrappali finds himself in the middle of domestic drama when he learns the woman he's dating, has a very upset husband. Also, when Sheldon rents his old room back for a quiet place to work, he drives Leonard crazy by being a model tenant.

Leonard's book raises questions, and Amy guest stars on the new Professor Proton show.

When Bernadette won't go into labor, the gang tries different tactics to get things started. Howard confronts Bernadette after Amy accidentally reveals she's already chosen their son's name.

Leonard jumps through hoops to help secure the perfect wedding venue for Sheldon and Amy. Also, Bernadette and Wolowitz have a hard time deciding who should stay at home with the kids and who should go back to work.

Bill Gates visits Penny's work, and the gang schemes to meet him. Hilarity ensues.

When Leonard learns Sheldon is the president of the tenants association, he decides to run against him. Also, Bernadette encourages Wolowitz and Koothrappali to find the owner of a drone after they find it in the backyard.

A brilliant but reclusive scientist, Doctor Wolcott, invites Sheldon to his cabin in the middle of nowhere, and Leonard, Raj and Howard go along for the trip. Also, Penny and Bernadette improvise after Amy doesn’t like the tame bachelorette party they planned for her.

Sheldon’s comic book store experiences changes when writer Neil Gaiman puts Stuart’s store on the map. Also, Koothrappali takes credit for Penny’s astronomical discovery, and friendships are threatened.

Sheldon goes to Vegas to win money for science. Also, Penny and Bernadette take Amy wedding dress shopping, but her terrible choice entangles them in a web of lies.

When Sheldon learns that his mother won’t attend his wedding unless he invites his brother, Georgie, he and Leonard travel to Texas to end a family feud. Also, the Wolowitz kids inadvertently infest Amy, Bernadette, Wolowitz and Koothrappali with pinkeye.

When Amy's parents and Sheldon's family arrive, everybody is focused to make sure all wedding arrangements go according to plan – everyone except the bride and groom.