The Care Bears live in a faraway place up in the clouds called Care-a-Lot. They travel around the world on Missions in Caring, whilst evil villains such as Professor Coldheart and Lord No Heart, try to thwart their plans.

Care Bears: Adventures in Care-a-lot is an animated television series by SD Entertainment, Cookie Jar Entertainment and Shari Lewis Enterprises that premiered on CBS's KEWLopolis line-up from September 15, 2007 to December 6, 2008, and is designed to be an immediate follow up to the movie Care Bears: Oopsy Does It!. It was the third Care Bears television series made and was produced by Sabella Dern Entertainment, the same company that made Care Bears: Oopsy Does It!. It features songs with music by Andy Street and lyrics by Judy Rothman.

Along with the other shows in the KEWLopolis block, this series fulfills the federal "E/I" requirements.

The Care Bears try to help kids and have fun in Care-a-Lot, but must contend with the antics of the mischievous Beastly and the young Beasties.

A group of lovable, huggable BFFs go on adventures and live that sweet Care Bear life. When a new adventure takes them to a strange new world, the bears have to lean on each other more than ever. Through friendship, courage and a little belly badge magic, the Care Bears continue their mission to spread caring and sharing to the world.

Care Bears and Cousins

Unlike the previous animation created by DIC and Nelvana in the 1980s, and as with Care Bears: Oopsy Does It!, this series features the new redesigned Care Bears with redesigned tummy symbols (also called "belly badges"). It also features a redesigned Care-a-lot. Additionally, there was initially no interaction with humans or other supernatural entities like those found in the previous iteration. Instead, as an immediate follow-up to Care Bears: Oopsy Does It!, the series inherits the sole villain from the movie, Grizzle, who has robots to do his bidding.

While other Care Bears do make appearances in the show, the series primarily focuses on five Care Bears in particular as seen on the Care Bears website: Cheer Bear, the new leader of the group, Share Bear, who's now a horticulturist, Grumpy Bear, now an inventor, Funshine Bear, now an energetic fun bear instead of a jokester, and introduced in Care Bears: Oopsy Does It!, Oopsy Bear. The show's theme song is performed by Kay Hanley.