Season 1 of Innocent Blue premiered on November 25, 2005.

Saeki Nozomi is a nurse that works at the hospital where her cousin stays due to an illness. She's married, but her husband is away on a business trip and thus can't take care of her horny attire. She really tries to be faithful to him, thus only flirting with her cousin whom she considers as her little brother...

The going-to-be nurse Ozaki Yumi also has her brother working at the hospital as a trainee. She has strong feelings for him and worries about him a lot but doesn't cross that line...