Detective Ruditsky relates the story of Nick Joseph, a small-time hood from Manhattan's Lower East Side, who rises from petty theft to become an ace contract killer for the syndicate's notorious Murder, Inc.

An immigrant woman tries to get Ruditsky to set her son on the straight and narrow. It seems as though he's been hanging around with a gang of hoodlums. Ruditsky gives it his best effort but it could be a tough sell.

Jane Cooper, recently paroled from prison, proves that she hasn't learned anything when she once again begins hanging around with underworld characters. Only this time it seems as though her mobster boyfriends keep dying off.

Cutie Jaffe, a small-time hood with big time ambitions, begins knocking over some of his brother-in-law's bootlegging trucks. Will Cutie rise in the underworld hierarchy or is he headed for a hard fall?

Dutch Schultz wants to bump off special prosecutor Thomas Dewey who has been after him. The syndicate bigwigs deny him permission to make the hit but the Dutchman proceeds with his plans anyway.

Small time racketeer Eddie Safronek plots revenge against the hoods who beat him up and left him for dead.

The underworld bribes police detective Harry Kramer in order to get him to withhold information in a case.

After a moll is found murdered, flashbacks tell her story and those of mobsters Tony Sappio and Big Ed Harper, who both loved not wisely but too well.

The body of a murdered young woman is dragged from the Harlem River and the police ascertain that she was killed because she knew too much regarding the activities of a bootlegging gang. Ruditsky then becomes puzzled when the attorney of the chief suspect insists on going to trial as quickly as possible.

Ex-convict Maxey Gorman gets a Machiavellian character named A.J. to finance his entry into the bootlegging business. The two men become partners but when the dough starts pouring in Maxie looks for a way to rid himself of A. J.

Muddy Kasoff has been renting automobiles for gangsters to use but he has been secretly tippin the cops. When the hoods discover that Muddy has been informing they have him killed. Ruditsky investigates and discovers that a cigar band might be an important clue.

When Ruditsky can't be bribed by a waterfront crime gang they attempt to frame him by making it look like he's on the take.

Ruditsky warns visiting high roller Big Ziggy to get out of town but before he can hit the road he get roped into a crooked poker game with three cardsharps.

Dick Wilson (2) as Game Boy Miles | Harry Arnie as Benny | Brad Trumbull (2) as O'Neill | Lou Herbert as Titanic Thompson | Jack Kruschen as Laughing Boy | John Vivyan as Big Ziggy

At a wild gangland party a young girl falls out of a window and is killed. When evidence shows that the girl was pushed, visiting Chicago mobster Ray Baker is arrested and charged with the crime. But Ruditsky has his doubts and thinks that the real culprit might be another mobster.

A judge is murdered right before a state crime commission is scheduled to take a look into his activities.

Ruditsky is temporarily assigned to duty in a Brooklyn precinct and must get the goods on a gang of hooligans who are pulling off a series of drug store robberies.

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