A New Orleans man is found in the street, bleeding from multiple gunshot wounds.

An EMS officer shares emotional news with his partner; firefighters respond to a call about a vehicle ablaze at a gas station.

After a quiet beginning of the evening, multiple calls virtually explode across the radio at once--and the most alarming code heard is for "Officer Shot." The overwhelming response to that call leaves EMT's Titus and Dan to endure an agonizing wait for police backup at the scene of a stabbing at a birthday party. Meanwhile, fire fighters respond to the scene of a burning car.

Police officers Victor and Lejon join a SWAT team operation hunting a homicide suspect. The fire department tries to save a man who fell into the Mississippi River. And for the EMTs, the calls tonight are as much about comforting victims as they are about saving them.

It's a full moon in New Orleans, and sure enough, all night long, the calls for the EMT's seem to get crazier and crazier: the victim of a machete hacking, the man whose finger is bitten off by a dog, the guy stabbed by a man dating his ex-wife. Meanwhile, two cops keep their perfect record of chasing down suspects in foot races intact, and a fire chief confronts his fear of rats.

Randy and Justin chase down a suspected car thief, while both EMT teams respond to emergency calls involving children in distress.

Police officers pursue suspected drug dealers, while Keeley saves a group of partiers from a violent schizophrenic.

It's New Year's in New Orleans and gun violence is rampant as Police and EMS deal with armed robberies and shootings. Plus, EMT Gavin returns to the job, and everyone celebrates a new addition to the family.