As Liz and the Task Force race to stop an imminent bombing by an elusive Blacklister, Red has an encounter that will change the trajectory of his life forever.

When multiple children are abducted under similar circumstances, the Task Force rushes to find the kidnapper. Meanwhile, Red goes on the hunt for a man who can find anything, while Liz considers a big change.

Presidential adviser Anna McMahon faces off with Cooper and the task force in a winner-takes-all race to locate the missing dossier containing details of a conspiracy against America.

As the president's true plan comes into focus, Liz and the task force fight to avert disaster. Red meets in secret with a man who holds information about his past.