The Task Force searches for a woman who specializes in hostile takeovers of criminal organizations, and may have intelligence connected to an international conspiracy involving presidential advisor Anna McMahon. Meanwhile, Aram enacts a daring plan to gain leverage over Red.

Cooper's moral compass is tested when an officer whom he served with as young man, long presumed to be dead, resurfaces as a POW.

Red and Liz investigate Orion Relocation Services, an organization that surreptitiously facilitates the disappearance and relocation of criminals. Meanwhile, Katarina delves into the memories of an old friend in order to get additional information about the Townsend Directive.

As Liz pushes a source for answers, Red and the task force grapple with the implications of her actions. Tensions boil over and a drastic action is taken, which will change Red and Liz's relationship forever.