O aficionado pelo paranormal Hank Galliston é arrastado para uma conspiração centenária com implicações apocalípticas nesta série, que começa com o sequestro da esposa de Hank de sua loja de relógios antigos por um homem que está a procura de um mapa do tesouro que pode estar ligado aos alemães nazistas de 1930.

Num explosivo começo da busca de Hank por sua esposa, Laila, ele e "Beck" quase morrem no confronto com White Vincent, que foge para a tundra canadense. Com mais perguntas do que respostas, Hank começa a busca pelo próximo relógio.

Com a determinação renovada em encontrar Laila, Hank volta da Índia, procurando respostas para novas pistas, enquanto Laila, que está sendo mantida refém por White Vincent, é obrigada a consertar o próximo relógio para ele.

White Vincent, ferido e em perigo, ainda está escondido e ainda mantendo Laila como refém. Sentindo sua vulnerabilidade e fraqueza, Laila o convence a deixá-la tratar de suas feridas, enquanto busca uma oportunidade para escapar.

Hank e Beck acabam mais uma vez ao lado de Vincent quando a próxima pista os leva até o Paraguai. Além disso, Hank fica intrigado com a revelação de sua conexão passada com Vincent e os mistérios relacionados à identidade verdadeira de Laila. Ao mesmo tempo, Arron e Rachel se encontram com o chefe da 41 Trust, apesar de suspeitarem de seus motivos.

Still searching for answers to the secrets of his past, Hank confronts his parents about his birth and childhood. Realizing they can no longer stay silent but fearful about how the truth could affect him, they fess up. But Hank immediately senses his parents are not being fully transparent. White Vincent revisits memories of his own childhood and the parallel lives he and Hank have lived. Meanwhile, the hunt for Laila and the next clock brings Beck, Paige, Arron and Rachel to Istanbul, Turkey. Hank searches for more information about his "doppelganger," Commandant Korbin Sturm, and makes an unlikely connection with a man who holds the key to more than Hank could have ever imagined.

Laila reaches out to Hank to share her side of the story and hopes he will forgive her. Still not totally trusting his wife, Hank teams with Laila to achieve a major breakthrough in their search for the True Cross. The Shepherds also know Hank is too valuable an asset and that they must enlist his help to get to the True Cross before the Pyrates do. Meanwhile, White Vincent, still under the employment of "Mother," discovers a clue of his own that also brings him even closer to the end.

Hank, Beck and Laila accelerate their search for the True Cross to the Faroe Islands. With renewed hope that her husband, Theo "Molars", is alive, Beck sets out to find him. Meanwhile back home, the Gallistons sense that Hank is in trouble and know the time has come to tell him the truth about his early years.

Hank, Beck and Laila are in the Faroe Islands, unsure if they will live or die at the hands of the Pyrates. Rachel shares some surprising news with Hank about his parents and the 41 Trust. Hank’s mother finally discloses the deeply painful secret she’s been holding all these years, and a dumbfounded Hank realizes his father is the missing piece to the puzzle.

Injured and disoriented from his recent car accident, Hank awakens on Plum Island in the hands of Melanie Lynch, a.k.a "Mother", and the 41 Trust. With the stakes higher than ever, Hank's father agrees to continue his work for "Mother" to ultimately save his son's life. While Beck frantically assembles a rescue team in an attempt to find Hank, Laila is impatient and secretly heads out on her own.

Everyone is on high alert, but their search for Rachel has met a dead end. However Hank has a dream which may contain clues that will guide the team to her remote location, and, hopefully help them stop the devious plan that "Mother" / Lynch has initiated in her "New Jerusalem.

Arriving at the entrance to New Jerusalem, Hank, Beck, Arron and the Shepherds know it's now or never to find Rachael and stop "Mother" / Lynch's plan before it's too late. But when the team unlock the doors, what they find is unimaginable. With faith shaken and time running out, can Hank and the team take down Lynch before it's too late? Or will life as we know it end in an instant? With everything resting on his shoulders, it's up to Hank Galliston to save the world.