Artistes récurrents de la saison 4

1. 

   Christy Carlson Romano

   Kim Possible (voice)

2. 

   Will Friedle

   Ron Stoppable (voice)

3. 

   Nancy Cartwright

   Rufus (voice)

4. 

   Tahj Mowry

   Wade Load (voice)

Vedettes invitées 12

1. 

   Jean Smart

   Dr. Ann Possible (voice)

2. 

   Nicole Sullivan

   Shego (voice)

3. 

   John DiMaggio

   Dr. Drakken / Student (voice)

4. 

   Amy Hill

   Dr. Wanda Wong (voice)

5. 

   Maurice LaMarche

   Dr. Harris / Dr. Kramer (voice)

6. 

   Rob Paulsen

   Dr. Cook / Student (voice)

7. 

   Kath Soucie

   Spirit Squad Weekly Interviewer (voice)

8. 

   Tara Strong

   Penny (voice)

9. 

   Patrick Warburton

   Steve Barkin (voice)

10. 

    Shaun Fleming

    Tim Possible / Jim Possible (voice)

11. 

    Kirsten Storms

    Bonnie Rockwaller (voice)

12. 

    Gary Cole

    Dr. James Possible (voice)

Équipe technique 3