The angels make good on a promise that Andrew made to a dying man---which involves uncovering the identity of a hospital employee posing as the angel of death, as well as restoring the faith of several terminal patients.
A salesman, whose ailing wife will be forced to leave a nursing home unless he can come up with $10,000, goes to Las Vegas and inadvertently sells his soul to an agent of the devil disguised as a casino manager.
When a young woman suffers a severe head trauma after being thrown from a horse, her husband struggles with whether to allow her heart to be donated to a 16-year-old girl who will die soon without a transplant.
Josie, an astronaut preparing for a mission aboard the space shuttle Discovery, struggles to cope with her God-fearing mother's death just days before the scheduled launch. Meanwhile, a sick child wants Josie to mail a letter to God.