10 giants from the world of comedy and cinema enter the LOL-house. Filled with enthusiasm to prove they can hold their laughs for 6 hours. Philippe Geubels and Jeroom Snelders send in two familiar faces, to ignite the fire. And the record of fastest laugh in the history of LOL is broken.

Philippe Geubels and Jeroom Snelders do not give the participants a moment of rest and physically demand the utmost from them. Bram finds it extra difficult when a good acquaintance of his enters the house. And there is even room for romance from an unexpected source.

Arjan strikes again, but he makes an unexpected victim. Ruben and Anniek have aimed their arrows at each other, with the pun as a weapon. Soumaya blows everyone away with her act and Leo has a very annoying accident. Philippe Geubels and Jeroom Snelders even use Eva Jinek to get a laugh from the comedians.

The group quickly shrinks and Phillipe and Jeroom are ruthless when they discover a smile. Rick Paul is finally allowed back into the house for a laugh. Bram hopes that self-torture will get people laughing and the battle of puns reaches a climax.

The final is within reach and the comedians call upon on their energy reserves to reach the finish line. An innocent plate of spaghetti makes victims and Henry and Bas do everything they can to make the remaining comedians laugh. Who is the winner of LOL?