With Sharona in New Jersey remarried to her ex-husband, Monk has been without an assistant for three months and it's time to find a new one--if only he could find a suitable applicant. When Natalie Teeger, a thirty-something widow with an eleven-year-old daughter, arrives at his house, he thinks she's applying for the job, but she's really been sent by Captain Stottlemeyer to get Monk's help--two men have broken into her apartment in the last few days and she had to kill the second one with scissors in self-defense. Examining Natalie's apartment, Monk finds a single clue, an unused fish net caught between the sofa cushions, suggesting that the intruders were trying to steal Mr. Henry, Julie's pet fish. But why would anyone want to steal a ninety-nine-cent red herring, er, crimson marblefish? A second clue surfaces when Lieutenant Disher finds a note in the dead perp's pocket reading ""2:30 Sea of Tranquility"" and Natalie identifies the Sea of Tranquility as an exhibit at the science mus

When Monk, Natalie, and Julie get stuck in a traffic jam after a multi-car collision blocks the freeway, Monk gets out of the car to investigate. He soon deduces from the absence of skid marks and other clues that the young man in the overturned Volkswagen that caused the pile-up was murdered and his body placed in the car to make his death look like an accident. But the highway patrolman in charge of the ""accident"" scene wants nothing to do with Monk (or the not-very-successful lawyer who has latched onto him), and the mountains blocking the signal prevent Monk from calling Captain Stottlemeyer for an authorization to investigate. Monk briefly returns to Natalie's car, where he finds Julie in need of a bathroom and Natalie nursing an injured wrist. Unfortunately for them, Monk's mind is on the fatality, and he returns to the Volkswagen. The angry officer gives him the victim's name and occupation (environmental activist), but he still refuses to listen to Monk's evidence. Meanwhile, t

With her daughter's school about to be closed as a cost-cutting measure, Natalie becomes a candidate in the upcoming school board election despite Monk's fears that she'll desert him if she wins. Natalie's frustrations with a jammed photocopier and other defective equipment bought at a police auction are dwarfed by fear for her life when a sniper fires into her campaign headquarters, further damaging the equipment and killing a security guard. The only clues to the identity of the sniper are an oddly folded note demanding that ""Natalie Teege"" withdraw from the election and a bullet from a semiautomatic rifle made in Russia. Suspicion falls on Natalie's opponent in the election, Harold Krenshaw, whom Monk knows as a fellow patient of Dr. Kroger's. Although Monk thinks that Krenshaw is lying about his friendship with Dr. Kroger and Krenshaw admits to being an excellent shot, Monk is sure that Krenshaw is innocent because he wouldn't misspell Natalie's name. When Krenshaw passes a polygra

After twenty-two-month-old Tommy Graser finds a severed finger and gives it to a policeman, Monk walks through the park with Tommy trying to retrace the child's steps. He finds no body or other incriminating evidence, but he does discover a surprising affection for the placid and intelligent toddler, who constantly repeats Monk's name and quietly submits to having his hands wiped when he touches ""nature."" A lab technician identifies the finger as that of a twenty-five-year-old man, and Monk deduces from a callus that the young man played the violin. After visiting the home of Daniel Carlyle, a musician who fits this description, Monk concludes that Daniel's mother and her other son, Jason, killed Daniel and that Jason is masquerading as his brother. Meanwhile, little Tommy is temporarily removed from the custody of his foster parents, and Monk surprises everyone, including himself, by volunteering to care for him for two weeks until his new adoptive parents can take him. With Tommy in

Monk appears to have met his match when a fellow detective shows up at a crime scene knowing all the answers.

Monk is reunited with his agoraphobic brother, Ambrose, after the murder of an armored car driver.

Monk feels too sick to work until a case gets him out of bed.

Needing a date for her brother's rehearsal dinner, Natalie resorts to asking Lt. Disher.

When an officer dies after drinking poisoned wine sent to Captain Stottlemeyer as a Christmas gift, the captain suspects Frank Prager, who tried to shoot him outside a bar several months earlier. Searching the crime scene for clues, Monk notes that the bullet holes seem to form a pattern, but neither he nor Stottlemeyer can figure out the message they're intended to convey. After trying unsuccessfully to talk with Prager's young daughter, Monk goes under cover as Santa Claus. This time he learns that Prager is hiding in a church with ""three ladies"" in front of it. But when Prager is caught and interrogated, it's clear that he had nothing to do with the poisoned wine. With the other suspects on Disher's list also eliminated, Monk and the captain are back to square one. But when Monk opens the card accompanying his gift from the Christmas party, he finds the clue that solves the case.

Monk is facing a crisis: he's down to five shirts. But Inspector No. 8, the only shirt inspector who can meet Monk's criteria for perfection, is not up to her usual standards. Sensing that something is wrong, Monk visits No. 8 on the job. The inspector, Maria Ortiz, informs him that her son, Pablo, has been imprisoned for murdering a fashion model, but she's certain that he's innnocent. Monk is chiefly concerned about his shirts, but Natalie persuades him to talk to Pablo because ""it's the right thing to do."" The conversation uncovers just one clue: Pablo can't read English. When Monk realizes that the killer must have been able to read an emergency exit sign, he's convinced that Pablo is innocent despite the DNA evidence used to convict him. With Stottlemeyer and Disher in tow, Monk and Natalie attempt to talk to the model's former roommate and the fashion designer she worked for, Julian Hodge. But now there's a new problem: Hodge wants thirteen-year-old Julie to model for him. Watching the rehearsal for a fashion show in which Julie will make her debut, Monk discovers a clue that points him to the real killer. When another supermodel is found dead, it's imperative that Monk find new evidence to prove his suspect guilty of both murders and set Pablo free--and for Natalie to get Julie away from the person committing the murders.

When Captain Stottlemeyer suspects that a suicide is really a murder, Monk confirms his suspicions by discovering that the victim, Joanne Raphelson, was too short to have used the stool she supposedly stood on to hang herself. But the next clue, the remains of an olive, a cherry, and a cocktail onion on a stirring stick, leads Monk to suspect that the murder was committed by an astronaut, Steve Wagner. A little research reveals a motive--Joanne was about to publish a book revealing that Wagner had abused her five years earlier. Now all Monk has to do is to prove that Wagner could commit the murder when he was in outer space.

Julie and her friends hire Monk to look into the suspicious death of their basketball coach.

When Monk's truck driving father rolls into town at Christmastime, Monk joins him on the road, where they stumble across a very peculiar mystery.

A missing millionaire suffering from leprosy comes out of hiding to hire Monk, who soon finds himself in the midst of a shadowy murder plot worthy of a classic Hollywood film noir. Episode originally aired in black and white.

A fun-loving everyman named Hal bumps into Monk, and the two become fast friends. For the first time in his life, Monk appears to have a buddy. But is Hal up to something?

When the mysterious “Six Way Killer” strikes in San Francisco, Monk matches his detective skills against the flashy forensic technology of a federal agent as they both pursue the murderer.

Monk tries to prove a sports agent is guilty of murder while helping Natalie’s teenage daughter with her love life.

Monk has trouble coping with new information that he finds out about his arch-rival, Harold Krenshaw.

Monk becomes a social pariah when he shoots a man dressed as Santa Claus. Then he must clear his name and foil a larger criminal plot, all in time for Christmas.

Monk searches for a killer who is apparently targeting women with the name Julie, a name which Natalie's daughter shares.

Monk must match wits against a grandmaster chess player that he suspects of murder.

When three homeless men seek Monk's services at the holidays, Natalie convinces him to investigate their friend's death; Stottlemeyer's faith is reawakened after a visit to a monastery fountain rids him of crippling pain.

Natalie suspects a theater critic is responsible for a murder, despite the fact that he was present to review her daughter Julie's play at the same time the victim died.

Monk is called to a murder at the location where he first heard of his wife's murder, and while Monk figures out who the assassin is, he doesn't know that the one who ordered the hit is also responsible for the death of Trudy. Knowing that Monk will eventually put all the pieces together, he orders Monk's death, and when all hope seems lost, Monk discovers something which could finally end his 12-year nightmare.

After listening to Trudy's last message, Monk finally discovers who killed his wife. Racing against time before he dies of poison, he must make a fateful decision.