Viewer mail inspires three stories in which Peter loses his bones, the Griffins gain superpowers, and Peter and his friends appear as eight-year-old "Little Rascals."

When Meg turns 18, Quagmire tries to make his move on her, but Peter tries to stop him.

Brian discovers that his new blind girlfriend can't stand dogs, and Peter cannot negotiate his way down the new staircase.

When Lois discovers that Stewie's sick playmate is being denied medical treatment because his parents are Christian Scientists, she decides to take matters into her own hands.

When Peter decides to become a famous actor, he becomes Tom Tucker's agent as his first step toward stardom. Meanwhile, Chris dates a girl who looks disturbingly like a member of the Griffin household.

Peter and Chris go to fat camp where they cross paths with a serial killer who targets overweight kids; an album cover frightens Stewie.

When Peter's favorite kiddie show gets canceled, he decides to create and star in his own. Meanwhile, Meg starts an internship for Dr. Hartman.

Meg's exciting European adventure comes to a halt when she is kidnapped; Stewie and Brian embark on an action-packed rescue mission..

Peter talks Joe into having an affair and gets into another epic fight with the giant chicken.

When Meg learns her crush is gay and interested in Chris, she uses her brother to get closer to him.

As the Griffin family is preparing for Christmas, Peter tells his own version of the Nativity story.

To boost Chris' self-esteem, Peter and Lois send him to space camp. When camp ends and the Griffins come to pick Chris up, they accidentally are launched into outer space, and it's up to Chris to land the clan safely back on earth.

Peter helps Joe fulfill his dream of getting a book published, only to take over as the writer. In the meantime, Brian develops an extreme thirst for exercise.

Peter becomes friends with a cool, handsome paramedic named Stryker Foxx. Wrapped up in his newfound "coolness," he soon dumps Quagmire, Joe and Cleveland.

Brian convinces Stewie to teach him how to invest in the stock market after learning Stewie has a knack for making money from it. Meanwhile, Peter, Quagmire, Cleveland, and Joe look after the Drunken Clam while Jerome is away.

Peter and his friends are sick of forgetting the million-dollar business ideas they come up with while drinking, so they strap on Joe's police body cams to record their every move. Meanwhile, Quagmire is trying to come to terms with an unexpected family development.

When Stewie receives a participation medal in his school's toddler games, he begins to question everything he has ever won. Meanwhile, Peter causes a fight between Lois' parents and must repair the damage he caused.

To celebrate Peter and Lois' wedding anniversary, the Griffins present their own versions of three well-known love stories.

Peter secretly gets a credit card and overspends the family money, so Lois grounds him. To plan the perfect escape, he builds a tunnel leading directly to The Drunken Clam.

Stewie's future life could not be going any better, living as a wealthy, old Mr. Burns-type man, until his retirement is interrupted by Brian, who brings news that Peter is dying.

With a newfound love for rocking out to Van Halen, Peter gets in a car accident and falls into a coma.