When a heat wave hits Quahog, Peter gets Brian to enter a dog show to win $500 so that the family can get a new air conditioner. When they argue over a trick gone bad, Brian walks out on the family and Peter replaces him with a cat. Brian struggles to assert his civil rights and soon ends up at the pound. Luckily, Peter is able to bail him out by bribing the judge.

A therapist tells Brian his carpet-wetting is the result of his repressed feelings for Lois.

Stewie misbehaves while visiting his grandparents.

Brian's first job in Hollywood is directing a pornographic film.

After losing at a swim competition, Stewie trys to eliminate his rival by blowing up a lifeguard tower. His plan backfires though, and Stewie has a near death experience that seems to change him.

Stewie cross-dresses in order to star in the American version of Jolly Farm Revue. Meanwhile, Peter makes Lois feel bad about her age.

In the 150th episode, Brian & Stewie get locked in a bank vault, they are forced to deal with each other on a whole new level.

Unlike any other FAMILY GUY episode, the acts will play out in real time as Brian and Stewie react to being locked in a small space with no baby food or martinis to keep them from losing their minds while they hatch an escape plan.

Feeling discouraged with the progress of his writing career, Brian decides to throw in the towel until Stewie become his manager and one of his books hits the bestseller list. But when the fame goes to his head, Brian gets a wake-up call from Bill Maher.

Stewie tries to be a big boy and steals Brian's car for a joy ride but lands in a bit of trouble. Meanwhile, Ryan Reynolds visits Quahog and becomes obsessed with Peter.

Stewie meets a female version of himself and falls in love; Peter and Quagmire step up their friendship.

Brian writes a play that becomes a hit in Quahog, but loses his confidence when he finds that the play Stewie wrote is better than his.

Brian decides he doesn't want to hang out with Stewie anymore, so Stewie tries to save their relationship by having a baby ... or seven ... by using Brian's DNA to impregnate himself. Meanwhile, Peter, Joe, Quagmire and Cleveland attempt to make a viral video.

When Stewie gets sent to see his school's child psychologist for a surprising session, he reveals major secrets about himself.

Stewie "breaks up with" Rupert after learning that he used to belong to Chris. Unable to get over his feelings of betrayal, Stewie decides to take action.