Elenco Principal da Temporada 5

1. 

   Seth MacFarlane

   Stan Smith / Roger (voice)

2. 

   Wendy Schaal

   Francine Smith (voice)

3. 

   Rachael MacFarlane

   Hayley Smith (voice)

4. 

   Scott Grimes

   Steve Smith (voice)

5. 

   Dee Bradley Baker

   Klaus (voice)

Convidados Especiais 12

1. 

   Neil Brown Jr.

   Scummy Guy (voice)

2. 

   Michael Croner

   Donkeyballs (voice)

3. Jeff Kauffmann

   Student (voice)

4. 

   Colin Ford

   Student (voice)

5. 

   Laraine Newman

   Nurse Margaret (voice)

6. Steve Hely

   Various (voice)

7. 

   Gary Anthony Williams

   Prisoner (voice)

8. 

   Andy Richter

   Drug Addict (voice)

9. Daisuke Suzuki

   Toshi Yoshida (voice)

10. 

    Eddie Kaye Thomas

    Barry Robinson (voice)

11. 

    Curtis Armstrong

    Snot Lonstein (voice)

12. 

    Jeff Fischer

    Jeff Fischer (voice)

Equipa Técnica 2