Coulson and his team are now wanted fugitives with limited resources, but that's not stopping them from keeping the world safe from powerful and unseen threats everywhere. However, with new members they hardly know, will S.H.I.E.L.D. ever be trusted again?

Hunted and running out of solutions, Phil Coulson puts his team right in the line of fire in the hopes of saving them all. But with General Glenn Talbot, HYDRA, and Carl Creel all on the attack, can they possibly survive? Meanwhile, a mysterious Doctor harbors some dangerous secrets that could destroy one of our core team members.

Coulson and his team race against HYDRA to get to Donnie Gill--a dangerous gifted with the ability to freeze objects--while Simmons is caught in the crossfire.

While on a mission to learn more about the secrets of the mysterious writing, Coulson finds himself attacked by the only person he can trust: Agent Melinda May. Meanwhile, the rest of the team is trapped in an explosive situation, and it's up to Fitz to save them--but is he up to it?

Coulson's team is up against the beautiful and deadly Bobbi Morse--Security Chief for HYDRA. Meanwhile, Skye's father forces Raina to reunite him with his daughter at any cost.

The world turns against S.H.I.E.L.D. when HYDRA impersonates them to attack The United Nations, and an unexpected enemy leads the charge to bring about their downfall.

The team discovers murder victims with the alien glyphs on them that Coulson's been etching. All of Coulson's secrets and lies come to a head.

Coulson and team find themselves in an epic face-off against HYDRA to uncover an ancient secret, while Ward kidnaps his brother, Senator Christian Ward, for a violent trip down memory lane.

S.H.I.E.L.D. discovers the ancient city before HYDRA, but uncovering the secrets may require one of Coulson's team to make the ultimate sacrifice. Meanwhile, Melinda May and Skye race to get to Raina before Daniel Whitehall takes her.

Coulson and Whitehall's forces meet in an explosive confrontation that dramatically alters everyone's fates. Meanwhile, Skye discovers shocking secrets about her past.

Coulson's team must deal with the consequences of their war with HYDRA as shocking revelations threaten to tear them apart, and HYDRA makes a dangerous move that may involve a traitor in S.H.I.E.L.D.'s midst.

Coulson and his team come to the aid of a confused Lady Sif, who has lost her memory after fighting with a mysterious warrior whose mission will send shockwaves through S.H.I.E.L.D. Meanwhile, Bobbi and Mack continue to hide their true mission from everyone close to them.

Cal seeks revenge on Coulson by assembling a team of Super Villains to destroy S.H.I.E.L.D. Meanwhile, May calls on renowned Dr. Andrew Garner, her charismatic ex-husband, with a crisis that threatens to tear the team apart.

Coulson and his team are still reeling from a shocking revelation that leaves the team fractured as they must decide what to do with one of their own. Meanwhile, Bobbi and Mack reveal their true allegiance to Hunter, while elsewhere, Ward and Agent 33 embark on a personal mission.

War comes to Coulson's doorstep in a way he never anticipated as shocking revelations are brought to light, and Skye struggles to control her new abilities but will soon make a decision that irrevocably changes her life.

As Robert Gonzales makes his move, Coulson must do whatever it takes to protect the future of S.H.I.E.L.D. Meanwhile Skye’s journey to control her powers takes a surprising turn when she meets the enigmatic Inhuman named Lincoln.

The story of Melinda May’s transformation into “The Cavalry” is revealed as she finds herself at a crossroads in the war between Coulson and Gonzales. As Skye learns more about her true heritage from Lincoln, the truth about the Inhumans will send her in a new direction.

A dangerous new alliance is formed as Coulson and Hunter turn to the last person anyone would expect – Grant Ward! As the war between S.H.I.E.L.D. factions continues, Skye and Lincoln will find themselves drawn into this conflict.

Gonzales and Coulson must find a way to put their differences aside and work together against HYDRA, even if it means teaming up with someone they don't trust.

Skye is torn between her loyalty to S.H.I.E.L.D. and her connection to the Inhumans as tensions rise between the groups -- and Coulson reveals a secret he's been hiding from even those closest to him.

S.H.I.E.L.D. puts everything on the line to survive a war that blurs the line between friend and foe. Coulson and his team will be forced to make shocking sacrifices that will leave their relationships and their world changed forever.

S.H.I.E.L.D. puts everything on the line to survive a war that blurs the line between friend and foe. Coulson and his team will be forced to make shocking sacrifices that will leave their relationships and their world changed forever.

When a new Inhuman is discovered, Coulson and the team have an encounter with another organization seeking powered people; Fitz goes to extreme measures to determine how to get Simmons back.

Fitz and the team enlist the aid of an Asgardian to unlock the secrets of the ancient Monolith that swallowed Simmons, and Agent May is at a crossroads in her personal and professional life.

Daisy, Mack and Coulson race to protect Lincoln as Rosalind’s team hunts down the Inhuman in their quest for powered people. Meanwhile, Hunter proves that there is no line that he will not cross to exact his revenge against Ward and HYDRA.

Coulson and the team search for the Inhuman who is killing other Inhumans. Meanwhile, May feels that Hunter's mission to take down Ward is getting too personal.

After her dramatic rescue from another planet, Simmons is still reeling from her ordeal and reveals how she had to fight for her life in a harsh new world.

The stakes get even higher as Hunter and May continue to go after Ward and HYDRA, and Daisy and Coulson begin to suspect that the ATCU may be keeping a big secret from S.H.I.E.L.D.

As Daisy and the team fight to protect Inhumans, S.H.I.E.L.D. discovers the shocking truth about one of their foes; Fitz helps Simmons recover information that could lead them back through the portal.

The S.H.I.E.L.D. team discovers dangerous truths about the ATCU, and Ward's plans to destroy S.H.I.E.L.D. take a surprising twist.

Ward's campaign for revenge brings the S.H.I.E.L.D. team to their knees, and Coulson proves he will do anything to settle the score.

A battle between HYDRA and S.H.I.E.L.D. will change Coulson's world; Fitz and Coulson take a huge risk.

In the aftermath of his trip to Maveth, Coulson is more determined than ever to get to Gideon Malick and put an end to HYDRA once and for all. Daisy and the team encounter more Inhumans who have powers like they've never seen before, but will they be friends or enemies of S.H.I.E.L.D.?

Coulson and General Talbot are forced to team up and attend a worldwide symposium on Inhumans, where they suspect Malick has an inside man. As the S.H.I.E.L.D. team gets closer to the truth, an unexpected traitor is revealed.

Bobbi and Hunter become ensnared in an assassination plot after tracking Malick to Russia. As S.H.I.E.L.D. races to save the lives on the line, the team is changed forever.

When a radical group called The Watchdogs emerges with plans to eliminate the Inhumans, Agent Mack and his brother become caught in the crossfire. Meanwhile, Simmons discovers a powerful chemical compound that could alter the future for Inhumans.

When Daisy gets a horrifying glimpse of the future, S.H.I.E.L.D. races to prove that fate is not fixed.

S.H.I.E.L.D. hunts for information on their dangerous new enemy, and a shameful secret from Malick's past is exposed, threatening to destroy his HYDRA legacy.

Agent Daisy Johnson must call upon the Secret Warriors for an inaugural mission that will leave no member unscathed, and S.H.I.E.L.D. learns more about Hive's powers, forcing them to question everyone they trust.

The S.H.I.E.L.D. team is left reeling and decimated as Hive continues to sway Inhumans to his side. But there is a sliver of hope as Agents Fitz and Simmons follow a lead that may be able to stop the maniacal Inhuman once and for all.

Coulson and his team race to combat Hive's control over the Inhumans, as their enemy's deadly plan for the human race is revealed.

With only two episodes left before S.H.I.E.L.D. loses one of their own, Daisy's prophecy ticks closer towards a major loss, as the aftermath of the events of Captain America: Civil War force S.H.I.E.L.D. to register the Inhumans.

It's a showdown a season in the making as S.H.I.E.L.D. takes on Hive, and when his master plan is finally revealed, the team must spring into action. Who will live and who will die?

It's a showdown a season in the making as S.H.I.E.L.D. takes on Hive, and when his master plan is finally revealed, the team must spring into action. Who will live and who will die?

Daisy has left S.H.I.E.L.D. and is trying to solve the mystery of a bunch of serial killings in the Los Angeles area. At the same time her old friends suspect her for the killings and are following her trail in an attempt to find her.

Daisy goes to battle Ghost Rider at a terrible cost, and Coulson faces the new Director, and his bold agenda surprises them all.

As Coulson, Mack and Fitz attempt to track down and neutralize a rogue group looking to end Inhuman Registration worldwide, Simmons and Dr. Radcliffe only have hours to save May before she succumbs forever to her mysterious illness.

As Ghost Rider's quest for vengeance brings him into an explosive confrontation with S.H.I.E.L.D., Coulson and Mack must rely on an unlikely ally in their time of desperate need; and Daisy reunites with a familiar face to stop the Watchdogs.

As Robbie Reyes struggles to control the Ghost Rider; S.H.I.E.L.D. infiltrates a high-security prison to unravel the secrets that haunt them all.

Robbie's shocking story on how he became Ghost Rider is finally discovered as Coulson and his team's lives hang in the balance.

With the loss of half the team, the remaining members search for answers as the clock counts down for Ghost Rider.

S.H.I.E.L.D. and Ghost Rider find themselves unlikely allies when the lives of all of Los Angeles hang in the balance.

Coulson is unaware of a dark secret May is hiding, even as the two grow closer; Aida is determined to find the Darkhold.

Separated from their team, Coulson and Mack discover a shocking secret about Mace, leaving all of S.H.I.E.L.D. in a precarious position.

May works to uncover the truth about what happened to her; Aida's next move puts everyone's life at risk.

Agents Sam and Billy Koenig are hunted down to get at the Darkhold book, and only Phil Coulson and the team can save them before the clock ticks out.

Daisy, Director Mace and the S.H.I.E.L.D. team must find a way to contain an explosive Inhuman. Meanwhile, Coulson and Mack come face-to-face with Radcliffe’s inspiration for Aida.

Mace fights for his life while Coulson and team find themselves in a deadly cat-and-mouse game as they attempt his rescue.

Suspicion turns to paranoia when the team doesn't know who can be trusted as more LMDs infiltrate S.H.I.E.L.D.

Daisy and Simmons uncover secrets and lies in a world gone mad. With HYDRA in control, they are our only hope to save everyone.

As Daisy and Simmons struggle to discover an escape route to the real world, the identity of the Inhuman leader of the Resistance is revealed.

The truth behind Fitz's turn could bring down all of S.H.I.E.L.D..

Daisy finds herself teamed up with an unlikely partner. Meanwhile, Aida prepares to put her ultimate end game into effect.

The clock is ticking for Daisy and Simmons to get the team out of the Framework, but not everyone is ready and willing to leave.

Coulson and the team's victory in the Framework is short-lived, as an even deadlier enemy looms against them all.

With the surprising emergence of Ghost Rider, Coulson and the team attempt to stop Aida from ending the world.

Coulson and the team find themselves stranded on a mysterious ship in outer space, and that's just the beginning of the nightmare to come.

Coulson and the team find themselves stranded on a mysterious ship in outer space, and that's just the beginning of the nightmare to come.

Daisy decides she will rescue Simmons, even if it means risking everything to do it.

Coulson and the team discover what their captors' true intentions are, and in space, escape is not an option.

With the surprising help of Lance Hunter, nothing will stop Fitz from finding the lost team as his incredible journey is revealed.

With Daisy's life on the line, an unexpected friend attempts to rescue her.

Just as the team reunites, they become prey to an undefeated Kree warrior bent on killing them all.

Coulson and the team discover that the most unexpected person from S.H.I.E.L.D.’s past may hold the key to stopping Earth’s destruction.

Mack, Yo-Yo, and Flint fight to keep everyone alive by starting a revolution against the Kree.

The team has one final chance to return to the timeline, but their actions may have deadly consequences.

Coulson and the team set out to rewrite the course of humanity's fate; they're unaware that their efforts will dramatically change one S.H.I.E.L.D. agent's life.

In the milestone 100th episode, Coulson finally reveals the mysterious deal he made with Ghost Rider, which will impact everyone on the team.

The team goes in search of Gravitonium in order to save the world.

As Fitz and Simmons race to find a way to seal the Rift, they are faced with one of their greatest fears manifested.

Coulson uncovers General Hale's true agenda, and it could be the end of the world if S.H.I.E.L.D. doesn't help her.

Coulson is forced to team up with surprising allies to save the world, while the S.H.I.E.L.D. team attempts to track down and rescue him.

While an agent's life hangs in the balance, Fitz, Simmons, and Yo-Yo attempt to neutralize a weapon that could play a role in Earth’s destruction.

The team must find a way to stop Ruby before the prophesied chain reaction that can destroy the Earth is put into motion.

Coulson and the team find themselves under siege at the Lighthouse.

A newly determined Talbot takes Coulson to meet the enemy and attempts to avert Earth's destruction.

Daisy's future as the Destroyer of Worlds could take a critical change.

Coulson's life or death is the challenge the team finds themselves in, as the wrong decision will cause the Destruction of Earth.