The 20th anniversary event kicks off with celebrity contestant Eric Stonestreet playing for Building Hope for Autism and Will Forte playing for The Pangea Network.

Will Forte continues his winning streak this week in support of The Pangea Network. Nikki Glaser will play for Rescue the Birds, including a never-before-seen historic moment in the show’s 20-year history.

Nikki Glaser continues her winning streak for Rescue the Birds. Jane Fonda takes the stage in support of her charity Fire Drill Friday’s, and Anthony Anderson plays for The Anderson Family Foundation.

Anthony Anderson continues his streak playing for The Anderson Family Foundation. Ike Barinholtz jumps in the hot seat playing for Uplift Family Services, and Hannibal Buress plays for Melvina Masterminds.

Hannibal Buress continues his run playing for Melvina Masterminds, while Catherine O’Hara steps up to play in support of Upward Bound House.

Catherine O’Hara continues her winning streak in support of Upward Bound House, and Dr. Phil plays in support of his charity When Georgia Smiled.

Lauren Lapkus continues her shot at the grand prize for the Crohn’s & Colitis Foundation, and Anderson Cooper plays for the Spikes K9 Fund.

Anderson Cooper continues his run on “Millionaire” for the Spikes K9 Fund and then swaps seats with Andy Cohen, filling in as his guest expert, as Cohen jumps in the hot seat for Planned Parenthood.