大学毕业后，布朗在区域剧院扮演了一系列角色。他还出现在许多电视节目中，例如ER，NYPD Blue，JAG，Boston Legal，Alias，Without A Trace，Supernatural和Third Watch。他曾是《饥饿饥饿》喜剧中的常客，还曾出演电影，包括《与埃文·麦格雷戈（Ewan McGregor）呆在一起》，《塔伊·迪格斯（Taye Diggs）与红糖》以及与大卫·杜乔夫尼（David Duchovny）和朱利安·摩尔（Julianne Moore）共同创作的《信任男人》（Trust the Man）。

他在电视连续剧中以反复出现的“超自然”出现，并在其中扮演吸血鬼猎人戈登·沃克。布朗在陆军妻子中饰演罗兰·伯顿（Roland Burton）博士。他还代表“感兴趣的人”侦探Cal Beecher。 2008年，他在伊莱·斯通（Eli Stone）的《忍耐》一集中饰演戴维·莫斯利（David Mosley）。 2016年，布朗出演了FX迷你剧《人民诉O.J.辛普森（Simpson）：美国犯罪故事的克里斯托弗·达登（Christopher Darden），为此他在黄金时段艾美奖颁奖典礼上获得了黄金时段艾美奖最佳连续剧或电影类最佳男配角奖。

在剧院里，布朗于2014年出演苏珊·洛瑞公园（Suzan-Lori Parks）的《奥德赛》中的英雄，这部作品的灵感来自《父亲从战争中回家》，在纽约的公共剧院里。

2007年6月，他与大学女友赖安·米歇尔·巴特（Ryan Michelle Bathe）结婚。他们有两个孩子。

Sterling Kelby Brown (born April 5, 1976) is an American actor. He is the recipient of various accolades, including three Primetime Emmy Awards, an Academy Award nomination, and a Golden Globe Award. He was included in Time magazine's list of the 100 most influential people in the world in 2018.

After graduating from college, Brown acted in a series of roles in the regional theater. He has also appeared on numerous television shows such as ER, NYPD Blue, JAG, Boston Legal, Alias, Without A Trace, Supernatural, and Third Watch. He was a regular in the Starved comedy and has also appeared in films, including Stay with Ewan McGregor, Brown Sugar with Taye Diggs and Trust the Man with David Duchovny and Julianne Moore.

He appeared in the television series as a recurring Supernatural, where he portrayed vampire hunter Gordon Walker. Brown played Dr. Roland Burton in Army Wives. He also represented Detective Cal Beecher in Person of Interest. In 2008, he played David Mosley in the episode of "Patience" by Eli Stone. In 2016, Brown starred in the FX miniseries The People v. O.J. Simpson: American Crime Story as Christopher Darden, for which he won the Primetime Emmy Award for Outstanding Supporting Actor in a Limited Series or Movie at the Primetime Emmy Awards.