Een jonge wees genaamd Biwa wordt opgevangen door de machtige Taira Clan, ook wel bekend als de Heike, nadat hun leider getuige is geweest van haar buitengewone paranormale gaven. Helaas voorspelt zij een toekomst vol bloedvergieten, geweld en burgeroorlog. Geïnspireerd door het 12e-eeuwse epische verhaal Heike Monogatari.

Rikuo Nura, is 3 parts human and a quarter Demon, lives in a house of spirits with his grandfather, The current clan head of the Nura youkai. Rikou is set to be the next clan head, despit the fact he dilikes his demon side. He soon come to terms with his demon blood and decides to take his position as young master of the Nura house. However there are those who will certainly not allow it to be easy.

Demi-Gods and Semi-Devils is a Chinese television series adapted from Louis Cha's novel of the same title. It was first aired in China on CCTV on 22 December 2003.