The Israeli-Jewish side of his family calls him Avram. The Palestinian-Muslim side Ibrahim. His first-generation American agnostic lawyer parents call him Abraham. But the 12-year-old kid from Brooklyn who loves food and cooking, prefers, well, Abe. Just Abe.

On an otherwise normal day, Étienne, a happily married man and a good father, sees something that stops him dead in his tracks: a gorgeous woman in a billowing red dress. Long after she has left his vision, her memory continues to haunt his mind. He falls instantly in love with her and tries everything to get to know her better. Helping Étienne snare his elusive lady in red are his three bumbling buddies, which all have secret affairs and/or cheat on their wives.

Christopher Gill is a psychotic killer who uses various disguises to trick and strangle his victims. Moe Brummel is a single and harassed New York City police detective who starts to get phone calls from the strangler and builds a strange alliance as a result. Kate Palmer is a swinging, hip tour guide who witnesses the strangler leaving her dead neighbor's apartment and sets her sights on the detective. Moe's live-in mother wishes her son would be a successful Jewish doctor like his big brother.