Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.
Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.
After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.
Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.
Thanks to his police officer father's efforts, Shawn Spencer spent his childhood developing a keen eye for detail (and a lasting dislike of his dad). Years later, Shawn's frequent tips to the police lead to him being falsely accused of a crime he solved. Now, Shawn has no choice but to use his abilities to perpetuate his cover story: psychic crime-solving powers, all the while dragging his best friend, his dad, and the police along for the ride.
Neal Caffrey, a con man, forger and thief, is captured after a three-year game of cat and mouse with the FBI. With only months left serving a four-year sentence, he escapes to look for Kate, his girlfriend. Peter Burke, the FBI agent who initially captured Caffrey, finds and returns him to prison. This time, Caffrey proposes a deal with the FBI, as part of a work-release program. After some hesitation, Burke agrees, and thus begins this unconventional arrangement where Caffrey helps Burke apprehend white collar criminals.
Both a gift and a curse, Graham has the extraordinary ability to think like his prey—he sees what they see, feels what they feel. But while Graham is pursuing an especially troubling, cannibalistic murderer, Special Agent Jack Crawford teams him with a highly respected psychiatrist – a man with a taste for the criminal minded – Dr. Hannibal Lecter.
Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.
Allison Dubois works in the District Attorney’s office using her natural intuition about people and her ability to communicate with the dead to help to solve crimes. Her dreams often give her clues to the whereabouts of missing people.
The world's leading deception researcher, Dr. Cal Lightman, studies facial expression, body language and tone of voice to determine when a person is lying and why, which helps law enforcement and government agencies uncover the truth. But his skills also make it easier for him to deceive others.
An unassuming mystery writer turned sleuth uses her professional insight to help solve real-life homicide cases.
Dr. Daniel Pierce, a neuroscientist and professor, is recruited to help the federal government crack difficult cases. His intimate knowledge of human behavior and masterful understanding of the mind give him an extraordinary ability to read people, but his eccentric view of the world and less-than-stellar social skills can often interfere with his work.
Jess Mastriani was a normal person who only wanted to take over her parents' restaurant in Indiana. But that changed when she was hit by lightning. After that she began seeing visions of missing people. Jess decides to use her newfound ability to be a consultant to the FBI, helping locate missing individuals. Eventually, she is hired by the bureau full-time and trained to become an agent, but her by-the-book nature sometimes clashes with the personality of her partner. Jess and her colleagues work out of the FBI's Washington, D.C., office.
The son of a notorious serial killer becomes an acclaimed criminal psychologist who uses his unique insight into how killers think to help the NYPD.
Cameron Black is the world's greatest illusionist. At least, that's what people used to call him—before his greatest secret was exposed and his career destroyed. Even worse, Cameron has good reason to believe this was no accident.
A retired FBI serial-profiler joins the mysterious Millennium Group, a team of underground ex-law enforcement experts dedicated to fighting against the ever-growing forces of evil and darkness in the world.
Toby Logan is a highly skilled paramedic with a secret – he can read minds. Toby never really knew his parents and grew up in foster care, this coupled with his secret, which he shares with no one, has made him a bit of a loner. Until now, Toby has kept his ability hidden, exploring its possibilities only with his long time mentor and confidante Dr. Ray Mercer.
The wise-cracking Fitz is a brilliant but flawed criminal psychologist with a remarkable insight into the criminal mind.
Driven by the fact that there are few things more dangerous than a prisoner who has just escaped, and tired of following protocol and resorting to outdated methods of law enforcement, veteran U.S. Marshals Charlie Duchamp and Ray Zancanelli are taking an unorthodox approach to their work: using former fugitives to catch fugitives.
Dr. Jacob Hood is a brilliant biophysicist and special science advisor to the government who investigates scientific crises and oddities. His crusade is to protect the substance of science against those who would abuse and misuse scientific discoveries for their own gain.