Season 1 of Stitch & Ai premiered on March 26, 2017.

After Stitch escapes his capture from the Jaboodies and the Woolagongs, he meets Ai, who takes him in. He helps her prevent her mysophobic aunt Daiyu from moving Ai from her mountain home to a city, while Ai helps Stitch ward off the pursuing Jaboodies and Woolagongs, as well as to help him find a shrine he's been seeing in some unusual visions. Jumba and Pleakley are also tasked with rescuing Stitch and bringing him to the United Galactic Federation, but they decide to let him stay with his new family and are reassigned to stay with them to help them and keep watch over him, especially since there are still lingering concerns about a secret program embedded in him that turns him into an unstoppable monstrosity.