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Lois is the perfect wife, but she's just discovered that her husband, Paul, is having yet another affair. At the urging of her neighbor, Lois hires a hitman to kill Paul, but the plan goes amok when Lois finds that Paul named his mistress as the benificiary of his insurance policy.

Guest-star Glenda Jackson portrays Dr. Doris Kruber, a talk radio psychiatrist who's taken hostage by Sally Trickleson, a Brooklyn woman who accuses Kruber's book of ruining her life.

Dr. Elaine Daniels learns that her ex-husband/coworker, Dr. Arthur Daniels (guest star Alex Rocco) has been dating a much younger woman. To make him jealous, Elaine flaunts a younger man under Arthur's nose. Meanwhile, the Daniels' coworkers make a bet on who will have sex first: the Daniels or the lab rats.