Kimble returns to his home town in Illinois after learning that his father, John Kimble, has suffered a heart attack and has donated his medical library to the University of Wisconsin and in the process of selling the family house. While Kimble hides out at the home of his sister Donna and her sympathetic husband Leonard, Kimble blames himself for his father's condition, but is more troubled by his younger brother Ray, whom belives Kimble is guilty and thinks he's to blame for ruining his life since people see Ray as ""the brother of a killer."" Meanwhile, Gerard arrives in town to search for Kimble and focuses on Donna and Leonard whom try to shake off the relentless detective long enough for Kimble to get out of town before Gerard finds him.

Kimble's sister Donna summons him home with a possible break in the case: a letter from James Eckhardt, a former U.S. Army captain whom also saw the one-armed man fleeing from the Kimble's house on the night of Helen's murder. Kimble meets with Eckhardt who agrees to help the fugitive out. Eckhardt's story seems strong enough to clear Kimble. But unknown to either men, another witness comes forward: a convict in prison for drug dealing, who reveals that he used to sell heroin to Eckhart for a Korean War battle wound and that Eckhardt was on his way to see him that night to buy some drugs, which is more than enough for Gerard to discredit Eckhardt's testimony.

After learning of the death of his father, Kimble contacts Donna and her husband Len Taft and wants to meet with them. Donna and Len drive to Fort Wayne, Indiana and check into a hotel under assumed names. But their rendezvous is threatned by Mike Ballinger, the former prosecuting attorney at Kimble's trial, who recognizes them and calls on Gerard to set up a trap.

This was the series finale. In the first part, the one-armed man whom Kimble has been pursuing has been arrested for a minor crime. Lt. Gerard tries to use this to lure Kimble out into the open. A woman who knows Kimble tries to help him. Kimble tries to see if this man is the one he is looking for but someone wires a bail bondsman some money to bail him out. KImble then visits the bail bondsman but finds him dead. He then goes through his papers and is shocked to see who sent the money. He then goes to see this person but Gerard catches and takes him in. As the one-armed man hops on a train, Kimble and Gerard are making their way back.

In the continuation of this story Kimble and Gerard are on a train for his hometown in Indiana. And Kimble then reveals that the person who sent the bail money is his brother-in-law Leonard Taft. Kimble doesn't think it was him but someone from his hometown did send the money and used his brother-in-law's name. The one armed-man calls the Tafts demanding that they meet with him, someone does go to the meeting but it's not Leonard Taft but the one-armed man assumes that he is, and says that he remebers him. Obviously this was the man who sent the money and the one-armed man is demanding more money which he doesn't have. Kimble and Gerard arrive at the Taft residence and talk to Len, who tells them that someone called claiming the same thing and arranged a meeting, Kimble ans Gerard arrive at the place and find some bullets. But for Gerard there is nothing more that can be done; they then go back to the Taft house so that Kimble can say good-bye to his sister, and it's at that moment tha