Kathryn Grayson, nascuda Zelma Kathryn Elisabeth Hedrick (Winston-Salem, Carolina del Nord, 9 de Febrer de 1922 – Los Angeles, Califòrnia, 17 de Febrer de 2010), va ser una actriu i soprano de coloratura nord-americana. Des dels dotze anys, Grayson es va formar com a cantant d'òpera. Va estar sota contracte amb Metro-Goldwyn-Mayer a principis de la dècada de 1940, i aviat va establir una carrera principalment gràcies al seu treball en musicals.

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Kathryn Grayson  (February 9, 1922 – February 17, 2010) was an American actress and operatic soprano singer. From the age of twelve, Grayson trained as an opera singer. She was under contract to MGM by the early 1940s, soon establishing a career principally through her work in musicals. After several supporting roles, she was a lead performer in such films as Thousands Cheer (1943), Anchors Aweigh (1945) with Frank Sinatra and Gene Kelly, and Show Boat (1951) and Kiss Me Kate (1953) (both with Howard Keel). When film musical production declined, she worked in theatre, appearing in Camelot (1962–1964). Later in the decade she performed in several operas, including La bohème, Madama Butterfly, Orpheus in the Underworld and La traviata.