Cast 29

1. 

   John Goodman

   The Dean (segment "Happy Birthday")

2. 

   Sydney Tamiia Poitier

   Hannah (segment "Happy Birthday")

3. 

   Beverly D'Angelo

   Bag Lady (segment "Happy Birthday")

4. 

   Christopher Lloyd

   Attorney Bum (segment "Happy Birthday")

5. 

   David Hyde Pierce

   Barney (segment "Happy Birthday")

6. 

   Caroline Rhea

   Monica (segment "Happy Birthday")

7. 

   Jenica Bergere

   Sally (segment "Happy Birthday")

8. 

   Ken Hudson Campbell

   Security Guard (segment "Happy Birthday")

9. Roman Danylo

   Donald (segment "Happy Birthday")

10. 

    Kimiko Gelman

    May Lee Ha (segment "Happy Birthday")

11. 

    Jean Kasem

    Nurse (segment "Happy Birthday")

12. 

    Taylor Negron

    Policeman (segment "Happy Birthday")

13. 

    Travis Wester

    Chute Boy (segment "Happy Birthday")

14. 

    Dondré Whitfield

    Man in Elevator (segment "Happy Birthday")

15. 

    Marissa Jaret Winokur

    Dean's Secretary (segment "Happy Birthday")

16. 

    Bruce Davison

    (segment "The Other Side")

17. 

    Anthony LaPaglia

    Dr. Maas (segment "The Other Side")

18. 

    Karen Sillas

    Anna (segment "The Other Side")

19. 

    Andie MacDowell

    Lisa (segment "Reaching Normal")

20. 

    Paul Rudd

    Kenneth (segment "Reaching Normal")

21. 

    Joey Lauren Adams

    Sarah (segment "Reaching Normal")

22. 

    Alan Rosenberg

    Frank (segment "Reaching Normal")

23. 

    Joel Grey

    Dr. Mensley (segment "Reaching Normal")

24. 

    Jolene Blalock

    Charlie's Wife (wraparound segments)

25. 

    Scott Lowell

    Charlie (wraparound segments)

26. 

    Stephen Tobolowsky

    Tom (wraparound segments)

27. 

    Kathleen Wilhoite

    Lucy (wraparound segments)

28. 

    Ellen DeGeneres

    Operator (segment "Reaching Normal") (uncredited)

29. 

    Helen Mirren

    Distinguished Woman (segment "Happy Birthday") (uncredited)

Crew 22