In a small Japanese town, Ko-Ko is appointed to the unenviable position of executioner. Knowing he must successfully perform before the appearance of the Mikado in a month's time, Ko-Ko finds a suitable victim in Nanki-Poo, who is distraught over his unrequited love for the maiden Yum-Yum. Nanki-Poo agrees to sacrifice his life if he is allowed to spend his remaining days with Yum-Yum, who is betrothed to Ko-Ko.

Brendan Byers III, one of the richest men in America, has been pronounced 4-F and can't serve his country in its war against Hitler. Byers does not take "No" for an answer and recruits other 4-F's to fight against Hitler.

Mr. Yunioshi: An Asian Perspective provides some insightful commentary of how far we've come concerning Asian characterizations in Hollywood movies from earlier eras.