A Hollywood agent persuades Kermit the Frog to pursue a career in Hollywood. On his way there he meets his future muppet crew while being chased by the desperate owner of a frog-leg restaurant!

When the Muppets graduate from Danhurst College, they take their song-filled senior revue to New York City, only to learn that it isn't easy to find a producer who's willing to back a show starring a frog and a pig. Of course, Kermit the Frog and Miss Piggy won't take no for an answer, launching a search for someone to take them to Broadway.

Kermit and Fozzie are newspaper reporters sent to London to interview Lady Holiday, a wealthy fashion designer whose priceless diamond necklace is stolen. Kermit meets and falls in love with her secretary, Miss Piggy. The jewel thieves strike again, and this time frame Miss Piggy. It's up to Kermit and Muppets to bring the real culprits to justice.