Finding himself in a new era, and approaching retirement, Indy wrestles with fitting into a world that seems to have outgrown him. But as the tentacles of an all-too-familiar evil return in the form of an old rival, Indy must don his hat and pick up his whip once more to make sure an ancient and powerful artifact doesn't fall into the wrong hands.

After freeing a young Bedouin girl from her unjust imprisonment in Jerusalem, an Australian adventuress, together with her devoted police detective friend, begins to unravel a decade-old mystery concerning priceless emeralds, an ancient curse and the disappearance of the girl's mother and massacre of her tribe.