Ava and Chloe discover -- for the first time -- that they both had a fling with the same guy. Unfortunately he's the fiancé of Emerson, their rich, new client who believes her man -- like her -- is a virgin. Meanwhile, Ava and her much younger husband go to a fertility specialist; thanks to a self-help book, Chloe realizes that no one has ever been ""that into her,"" and Lola, who recently divorced after discovering her husband is gay, tries to re-enter the dating world.

To help cheer up a grief-stricken Lola as she gets over the death of her pet chicken, Ava invites her and the girls over to her apartment. They commiserate about what's missing in their lives and, after drowning their sorrows, are horrified the next morning to learn that each of them dialed someone on their cell phones while drunk. While Chloe thought she had called her eighth-grade boyfriend, she actually dialed the number of her highly-critical, overbearing mother who pays an unexpected visit.

Through mutual encouragement, the women decide it's time to take some risks that they wouldn't ordinarily take. When Ava's much-younger husband gets an acting job playing a teenager, she decides it's time to be honest with him about her real age. Chloe starts dating a man who is trying to fatten her up, but to her delight she finds it quite liberating. Meanwhile Lola begins therapy sessions with Sellers to find out why she's attracted to gay men, and Emerson must convince her wealthy parents to let her work at the real estate office.