McCall races to save the team after they're put into extreme danger by her former CIA colleague Michelle Chambers while she discovers the truth behind the CIA withdrawal in Venezuela that led to the death of one of her friends.

After a young girl is struck by a car in an illegal street race, McCall tracks down the person responsible for the hit-and-run. Meanwhile, Dee contemplates the idea of following in her mother's footsteps to join the armed forces.

After a high-powered real estate developer is killed by a moving subway train, his widow hires McCall to investigate his death. Meanwhile, Aunt Vi and Dee visit an old neighbor living in a nursing home who may need their help.

After Mel is reunited with her brother, McCall helps him blow the whistle on his former unit's unethical practices before it's too late. Aunt Vi and Trish's relationship becomes fractured by Vi's need to protect McCall's true identity.

When a former Chinese MSS agent is poisoned and comes to McCall for help, McCall tracks down the perpetrators and the antidote. Meanwhile, Aunt Vi encourages Dee to protest against a well-known climate change denier.

Dee asks McCall to help find her transgender friend when the teen goes missing. Meanwhile, Dante is surprised when Big Ben's parole officer approaches him to chaperone his father for an out-of-state trip.

McCall races to help Dante and Big Ben after they are ambushed by a group of suspicious attackers and a major family secret is revealed. Meanwhile, at a party celebrating 50 years of hip-hop, Aunt Vi tries to maintain her status as the reigning queen of the annual cobbler baking contest and Dee suspects a mutual friend may have stolen prize money.

When a conman from Dante’s past attacks a prison transport, McCall and the team race to take him down. Meanwhile, Aunt Vi and Dee’s girls’ trip is suddenly derailed when they find a woman squatting in their home, and Harry risks his relationship with Mel when Fisk pulls him deeper into his secret mission.

The team races against the clock after Mel is kidnapped by a member of her veteran support group and his older brother. Meanwhile, Dante is offered a position with the NYPD's Special Investigation Unit in Los Angeles.