When a young man accidentally shoots a cop in self-defense and goes on the run, the team members find themselves in a moral dilemma on the best way to carry out justice. Also, Barnes and her wife struggle with their plans to have another child.

Jess and the Most Wanted team head to Tennessee to track down an undercover DEA agent who appears to have turned dirty amid a major drug ring operation. Also, Sarah wonders if it was a mistake to move in with Jess and Tali so soon.

The team hunts for a young man who is using napalm-style bombs to attack his targets. Also, with Tali away, Jess and Sarah begin to adjust to their empty nest.

The team searches for a businessman wanted for murder and an embezzlement scheme. Also, Jess takes advantage of his empty nest to properly court Sarah.

As the team chases after the suspects behind an explosion at an Ohio energy plant, they are led towards a major crypto company with enemies looking to take it down; Remy and his sister close a chapter in their lives.

The Fugitive Task Force searches for a missing migrant teen they believe was lured into unlawful work by a dangerous man. Also, Remy learns of a previously undisclosed witness in his brother’s murder case.

The Fugitive Task Force launches into full gear after multiple bombings appear to be targeting retired NYPD officers. Also, Ray decides he's ready to take the next step in his relationship with Cora.