Maggie and OA lead the search for an abducted former biological weapons chemist.

Maggie and OA are on a mission to find a couple who are behind a spree of violent armed robberies that resulted in the death of an off-duty police officer.

A loving husband and father of two, Jim Russo, is kidnapped after accidentally getting involved in illegal dealings far beyond what he imagined. Also, Jubal must make a difficult decision regarding his family and their future.

A former kidnapping victim is linked to a series of murders that includes the daughter of an NYPD detective. Also, Kristen begins to doubt her ability as an agent after a training exercise leaves her shaken.

After a truck filled with armour-piercing rifles is hijacked, the team works to discover who stole it, and what they have planned for the stolen weapons. A friend from OA's past returns to help with the case, but OA isn't sure he can trust him.

As the team searches for a young girl who was kidnapped from a cabin during a family vacation, they discover that the abduction may be tied to a skeleton in her family's closet. Also, Maggie questions her relationship with Nestor when she learns he hasn't been completely honest with her.

The team must track down two assailants who wear animal masks while committing armed robberies, with the latest leaving an off-duty 26 Fed security guard dead. Also, Tiffany and Scola butt heads on whether or not to accept the local NYPD’s offer to help in the investigation.

When five prominent men are killed at a trendy New York City restaurant, the team’s investigation brings them into contact with a lieutenant in Antonio Vargas’ cartel, triggering a long-awaited showdown between Isobel and Vargas.

Maggie, OA and the team must stop a hacker who is disabling life-saving equipment in several New York City hospitals. Jubal's son waits for important surgery at one of the impacted hospitals.

After a suburban woman is kidnapped from her home, the team looks into trysts on both sides of a seemingly perfect marriage. Also, OA feels pressure from Mona to make changes in his career path.

Maggie goes under cover working in a bar to investigate an anti-government group that regularly gathers there; a single father on the periphery of the group begins to fear he's in danger of becoming collateral damage.

When a morning show host is murdered inside her home, the team tracks the killer, who they realize is targeting powerful women. Also, things become awkward for Scola when Special Agent Nina Chase becomes part of the team during Maggie's recovery.

As the team works to rescue a 5-year-old kidnapping victim, Scola suspects the boy’s mother isn’t being forthcoming about why her son was targeted. Also, Nina struggles to open up to Scola about matters in their relationship.

The abduction of a young woman leads the team back to a cold case from 18 years ago, which pushes Isobel to reconnect with her old partner Jake and take another shot at solving one of her first cases in the bureau.