When a prison bus crashes, all units must respond as some inmates face severe injuries while others seek an opportunity to flee. In the wake of the accident, Officer Nolan tries to impress an FBI hostage negotiator while tracking down an escaped convict.

An emergency alert of an impending missile attack sends Los Angeles into chaos and uncertainty, while the officers each try to keep the peace and deal with their own disasters.

Officers Nolan and Bradford hope they can de-escalate a drug war before any innocent lives are lost. Meanwhile, Officer Harper hopes she can get Officer Chen ready to go undercover.