Katy Brand's Big Ass Show is a British comedy programme on ITV2.

The show features comedian Katy Brand in skits of real life situations and stereotypes, as well and celebrities such as Amy Winehouse, Lily Allen, Lady Gaga, Angelina Jolie, Adele and Kate Winslet.

The second series began on 2 September 2008. The series is carried in Canada on CBC's bold channel as of October 2008, and in Portugal on RTP2, each Sunday latenights at 11:50 pm, on the "Britcom" strand.

Her comic clips in the second series include Princess Beatrice of York, Kate Moss, Leona Lewis, Jesus, The Queen and Billie Piper's Secret Diary of a Call Girl.

A Christmas special called Katy Brand's Big Ass Songs of 2008 aired on 13 December 2008.

The third and final series began on 10 September 2009 and ended on 15 October 2009.

When Katy appeared on Justin Lee Collins: Good Times she stated that there would be no more series of Katy Brand's Big Ass Show and that she would end the show with a live tour throughout April 2010.