Pravidelné obsazení sezóny 5

1. 

   Benedict Cumberbatch

   Patrick Melrose

2. 

   Jennifer Jason Leigh

   Eleanor Melrose

3. 

   Hugo Weaving

   David Melrose

4. 

   Sebastian Maltz

   Young Patrick Melrose

5. 

   Jessica Raine

   Julia

Hostující obsazení epizody 25

1. 

   Jennifer Armour

   Border Control Officer

2. 

   Allison Williams

   Marianne Banks

3. 

   Richard Brake

   Mark

4. David Mills

   Hotel Receptionist

5. 

   Oengus MacNamara

   Bellboy

6. 

   Dempsey Bovell

   Drug Dealer 2

7. 

   Kevin Layne

   Shades

8. 

   Charley Palmer Rothwell

   Drug Dealer 1

9. Janine Harouni

   Funeral Parlour Receptionist

10. 

    Michael Levi Harris

    Funeral Parlour Waiter

11. 

    Apple Brook

    Elderly Mourner

12. 

    Kerry Shale

    Funeral Director

13. 

    Cory Peterson

    Restaurant Waiter

14. Andrea Davy

    Mrs. Willy

15. 

    Philip Arditti

    Pierre

16. 

    Matthew Marsh

    Ballentine Morgan

17. 

    Nancy Crane

    Nancy Banks

18. 

    Eben Young

    Jerry Banks

19. 

    Gary Beadle

    Chilly Willy

20. 

    Morfydd Clark

    Debbie Hickman

21. 

    John Standing

    George Watford

22. 

    Eric Meyers

    Key Club Member

23. 

    Prasanna Puwanarajah

    Johnny

24. 

    Pip Torrens

    Nicolas Pratt

25. 

    Indira Varma

    Anne Moore

Štáb 3