The SWAT team works with Lieutenant Piper Lynch, a senior LAPD Hollywood Division officer, when the mayor assigns her to oversee city departments joining forces to stop a serial bomber using drones as detonation devices. Also, just as Hondo settles into legal guardianship of his teen charge, Darryl, his home life becomes more complicated when his estranged father unexpectedly moves in.

Lt. Lynch pulls the SWAT team’s focus when the mayor tasks her with enacting a departmental review of the squad right as they pursue the unstable and dangerous fugitive leader of an infamous doomsday cult. Meanwhile, Luca asks the team to invest in his new passion project, a Guatemalan food truck.

The SWAT team bumps heads with Lt. Lynch when she signs them up for an off-book undercover operation to take down a local gang printing counterfeit money, without giving them enough time to prepare for the mission. Also, tensions rise at home for Hondo as his parents’ strained relationship becomes worse.

Deacon’s family gets caught in the crosshairs of a drug cartel when he and the SWAT team aim to bring down its leader, a former foreign rebel force leader running drugs in plain sight via a local flower market. Also, Hondo receives troubling news regarding his father, and Tan is forced to go before an internal review board due to his girlfriend’s indiscretion.

Street reconnects with his estranged foster brother, Nate, to help a joint investigation between SWAT and the Long Beach Police Department when criminals steal a mass arsenal of LAPD assault rifles. Also, Hondo finds himself at odds with his father over the elder man’s declining health, and Luca is overwhelmed when the entire team reconsiders becoming investors in his food truck,

The Harrelsons engage in a tense family reunion when Hondo’s older sister, Winnie, begrudgingly arrives in Los Angeles to see their sick father for the first time in decades. Also, the SWAT team searches for an abducted Middle Eastern human rights activist; Luca’s food truck business hits a snag; and Street worries that dating Captain Hick’s daughter, Molly, will negatively impact his career.

The SWAT team joins forces with the Los Angeles Organized Crime division to recover an officer abducted during a failed undercover operation. Also, Chris struggles with how to comfort the kidnapped officer’s parents when she is restricted from giving them certain details of the investigation.

The SWAT team’s task to provide security for a warlord is threatened by assassins determined to take him out before he’s extradited by the International Criminal Court. Also, Hondo’s father, Daniel Sr., tries to make amends to his mother, Charice, Street’s foster brother, Nate, asks for his help with a corrupt boss and Deacon reluctantly explores therapy for his daughter, Lila.

Hondo and the SWAT team rally to support Street when he puts his life on the line to help his foster brother Nate break away from a drug ring.

Hondo, Deacon, Tan and Commander Hicks engage in a manhunt across Tokyo when they escort an extradited fugitive to Japan, where he escapes local custody. Back in Los Angeles, the rest of SWAT search for any contacts the criminal cultivated while hiding out in Los Angeles, and Street isolates himself from the team as he deals with family issues.

The SWAT team searches for a link between the seemingly unconnected victims of a lone gunman targeting women. Also, Luca assists with a homicide investigation in his neighborhood; Lieutenant Lynch pushes Chris to do a news interview; and Hondo reaches a juncture in his relationship with Nichelle.

Deacon’s second job working private security at a high-profile boxing match places the SWAT team in the middle of a kidnapping case when a prize fighter’s wife is abducted. Also, Hondo’s young charge, Darryl, becomes frustrated with his lack of paternal rights regarding his infant son, and Tan prepares to introduce his critical mother to his girlfriend, Bonnie.

The SWAT team must protect a hotel full of civilians after a joint task force mission with the LAPD Gang Division goes wrong, and the city’s most dangerous gang leaders scatter across the building to find an escape. Also, Luca’s efforts to coordinate the team’s mission are complicated when his brother, Terry, a freelance stringer reporter, crosses police lines to shoot footage.

Hondo and the SWAT team race to save Buck, their former unit leader, when he goes off grid and they fear he plans to harm himself. Flashbacks reveal the search for Buck, which coincides with one of the team’s most brutal missions, as each team member receives counseling and discusses the untold mental and emotional difficulties inherent to working in SWAT.

The SWAT team searches for an escaped convict who plans to kill Tan and every member of law enforcement who helped put him in prison years ago. Also, Chris comes face to face with internal corruption when she arrests a young man who is given a free pass due to his powerful father, and a surprise visit by Hondo’s sister, Winnie, puts pressure on his relationship with Nichelle.

The SWAT team pursues a couple reminiscent of Bonnie and Clyde, when the duo goes on the run and on the hunt for a set of rare chest pieces worth millions. Also, Hondo and Darryl are surprised when Darryl’s ex-girlfriend visits with his young son, and Luca confronts his fear of failing his requalification to return to the field as he helps Kelly, his mentee.

The SWAT team searches for a group of drug smugglers who crash a plane in a Los Angeles suburb and scatter, after a joint mission with the DEA to stop the shipment goes awry. Also, Hondo tries to make amends with Nichelle, Luca experiences anxiety about his return to the field, and Deacon hesitates when asked to speak to a group of recruits about mental health.

Hondo, his father Daniel Sr. and his teen charge Darryl confront the history of racial tension in Los Angeles between law enforcement and the Black community, through flashbacks to the city in 1992 following the Rodney King verdict. Also, the SWAT team pursues El Diablo’s scattered drug cartel hiding in the city and a Jihadist group detonating bombs in coordinated attacks,

Hondo is conflicted when the mayor asks him to be the public face of a new outreach campaign meant to improve the LAPD's stature within the Black community. Also, the team's search for a lone bomber reminds Tan of a difficult chapter in his childhood, and Chris pushes herself even further to surpass Street and Tan in a SWAT leadership competition.

A tragic mission leads each member of the SWAT team to contend with their emotional distress in varied ways.

The team races to rescue victims of a sex trafficking ring that is preying on disenfranchised women. Also, Hondo finds himself at odds with Leroy and Darryl over the future of their business, and Street confronts Chris about meeting with his hospitalized mom.

The bombing of a Los Angeles police station puts the city on edge, leading the team to a final showdown with a group of domestic extremists. Also, Hondo faces the fallout from a bold decision that threatens his future, and Tan takes a big step in his personal life.