El Chapo and his men find the perfect place to build the world's largest drug lab. Don Sol gives Franco money and demands that he stay away from him, but he rejects it. DEA analysis shows that the Sinaloa cartel has rapidly expanded operations in the entire world.

Don Sol agrees to marry Berta to fulfill his political goals. Men of El Chapo confess to the US police that he was about to put a bomb in the embassy. Mayel is arrested, Joaquin stops the Malaysia operations in exchange for his release.

El Chapo sends Elba to live in another house so no one will hurt her. Don Sol and El Chapo make an agreement to make the police believe that he is trying to catch him and that both can fulfill their plans. A journalist of El Popular investigates allegations that Don Sol is protecting El Chapo.

Isidoro leaves a message for El Chapo demanding him to defend his place, since he is determined to be his worst enemy. Elba tells El Chapo that she is expecting twins.

El Chapo asks his men to do social work on behalf of Esteban Prieto so that people vote for him. Esteban wins the elections and Don Sol is appointed Secretary of Governance.

El Chapo and his men steal Isidoro's merchandise and destroy his laboratory. The army tries to catch El Chapo, but he manages to escape and Don Sol gets upset because he knows that it will be more complicated now to arrest him.

El Chapo is arrested by the army and Don Sol informs Esteban that the world will find out that they caught the most important drug trafficker in the world. Don Sol meets Franco and his wife discovers him.

El Chapo begins to get contacts in jail to avoid being extradited and escape. Esteban asks his wife to publicly clarify the problem he has with one of his properties and Don Sol is enraged when he realizes it.

Damaso and Quino fight to take over the organization of El Chapo. El Chapo learns about the problems between Damaso and Quino and demands that they respect each other, but he knows that he must rush to escape from prison or they could ruin the organization.

The men of El Chapo begin to dig the tunnel so he can escape. El Chapo manages to escape with the help of his men and the contacts of Don Sol.

El Chapo makes clear the distribution of his power if he could not take over the organization. Franco tells Don Sol that he will go to work in another state because he is tired of having to hide so nobody knows about their relationship.

Esteban demands from Don Sol that he resign, he refuses and threatens to confess that Chapo paid for his campaign and that he helped him escape from prison. Don Sol suspects that El Chapo will hide with Marcelo and sends the army to look for him. While Gortari wants to appoint his daughter as presidential candidate but eventually Don Sol earns his trust and is himself appointed.