Rachael Leigh Cook smashes more than eggs in her latest This Is Your Brain on Drugs public service announcement. Optimus Prime, leader of the Autobots, falls prey to prostate cancer. The outcome is never in doubt during "World's Most One-Sided Fistfights Caught on Film." Outtakes from The Dukes of Hazzard, The X-Files, Battlestar Galactica and more come to light in "Bloopers."

Voltron engages in an old-school dance-off in "You Got Robo-Served." The secret lives of nature's most fascinating beasts are exposed in "Secrets of the Animal Kingdom." Testicles are terrorized in "Ode to the Nut Shot." Walt Disney's severed head with its giant robotic spider-body attacks Cuba. See how much the kids are horrified in "Scary Barney"

The animals Noah left behind try to survive the flood in their very own ark. Enjoy instant nostalgia with "That '00s Show." Mrs. McNally's third-graders produce an animated abomination in "The Best Cowboy." The world's most famous cars, from KITT to the General Lee and even Mario karts, race against each other in "3 Fast 3 Furious."

America sends Harrison Ford and Aerosmith into space to take out a killer asteroid in "Meteorgeddon." Household animals take to the slopes for "Winter Pet Games." Chucky from the Child's Play series takes on the cutesy Lettuce Head Kids in the opening to season 8 of Buffy the Vampire Slayer. The Muppet Show's band is spotlighted in "Behind the Music: Electric Mayhem."

The tooth fairy stumbles into domestic violence and murder in "Tooth and Consequences." The world's most diabolical supervillains get stuck in traffic. More of television's greatest screw-ups, from CSI to Mister Rogers' Neighborhood and Pro-sports, are highlighted in "Bloopers."

The secrets of The Crying Game, Sleepaway Camp, Star Wars and The Village are exposed in "Welcome to the Spoilers." The Teen Titans strengthen their roster by adding Beavis and Butt-head. Travel back in time to witness Benny Hill's funeral. The Great Pumpkin of Peanuts fame finally shows. Too bad he becomes murderous, and goes on a killing spree.

A teenage girl gets a fashion makeover in "Pimp My Sister." The Surreal Life gang gets sent on a mission to destroy an enchanted ring. Debbie Does Dallas gets re-told with the world's cheapest puppets in "Exhausted Budget Theater." Geeks and nerds collide when a science fiction convention erupts into war.

Seven of the world's greatest heroes stop being polite and start getting real in "The Real World: Metropolis." Icons from Star Trek and Tiger Beat alike unite for canned sitcom laughs in "Two Kirks, a Khan and a Pizza Place." Jesus Christ hunts down his greatest nemesis, Tarantino-style in "Kill Bunny." The hottest game show from Japan is here: "Who Poop Last?!" The legends of rock 'n' roll return from beyond the grave to haunt the "Zombie Idol" reality show.

The roller-coaster celebrity life of the Hulk is profiled in "Hollywood Spotlight." The Masters of the Universe are rocked by a Paris Hilton-style sex tape. Michael Jackson returns from space to confront his n'er-do-well alter ego in "Where's Michael?"

William Shatner's toupee has adventures the action star can only dream of. Heaven is not all it is cracked up to be in "Can We Handle the Truth?" Hilary Duff's new film combines history and teen drama in an updated "The Diary of Anne Frank." The fates of the greatest action figure toy lines from decades past are exposed in "Where Are They Now?" with host Michael Moore.

"The World's Most One-Sided Fistfights" get wild at Mardi Gras. Benjamin Franklin grapples with historical figures like the Wright brothers and Mahatma Gandhi in "Educational Wrestling Federation." Oprah Winfrey fulfills all her viewers' fondest wishes...almost. A man in a public restroom encounters the terror known as "Dumplestiltskin." "12 Angry Little People" deliberate a crime most heinous.

A teenage girl gets crazy about everyone around her. The world's most famous monkey bursts loose on Skull Island in "Ding Dong, King Kong." Scandalous Hollywood news and gossip get the Pat O'Brien treatment. A father pigeon teaches his son to poop in a snorkel to make things wild. The Smurfs are terrorized by a murderer who kills based on the seven deadly sins in "Murder in Smurf Town X."

Sailor Moon encounters a bone-chilling villain. A nerd wins a date with Scarlett Johansson. "Welcome to the Terror Drome" showcases inner-office machinations at the headquarters of G.I. Joe's nemesis Cobra. "America's Most Tragic Home Videos" will make you laugh and cry.

Michael Knight's talking car parties hard in "KITT's Day Out." A brawl rocks the nursing home in "Grandma Fu." Mary-Kate and Ashley Olsen unite to fight a rampaging dragon. George Jetson's murder takes center stage in "Unsolved Case Files: I, Rosie."

Jaws gets a special edition DVD. A drug operation at the North Pole is revealed in "Unsolved Case Files: Claus & Effect." The A-Team solves its problems with maximum firepower and minimal intelligence.

A new video game is taking video games by storm, "Codename: The Abortionator." A video dating experience a la The Ring scares a potential suitor. A man runs away from an Oriental masseuse looking for a "happy ending". Keanu Reeves, Christopher Walken, and William Shatner want you to buy his special brand of sausage. The Scooby-Doo gang encounters Jason Voorhees at Camp Crystal Lake.

It's Alien vs. Predator on the battleground of love in a special episode of "First Date". Frogger creates a huge car wreck in this episode. See what the future holds in the Carousel of Tomorrow. Popeye experiences a world without his hamburger-leeching friend in "It's a Wimpy-Filled Life." The modern video game Halo invades the old-school classic Donkey Kong. The cereal spokesbunny Stix Rabbit finds himself a new way to make a buck.

Dean Devlin and Roland Emmerich re-make Godzilla...again. A crime-fighting monkey saves monkeys from a monkey supervillain. An average fellow named Doug wakes up in the world of the Huggytime Bears. Freddy Krueger, Jason Voorhees, Leatherface, Pinhead, Ghostface and Michael Myers sign on for the reality show "Big Brother".

Napoleon Bonamite pops up as a famous figure from history. Fizzing candy has terrible repercussions for young Mikey. Pennywise the Clown explains why everything floats in the sewers. A weakling turns into the "King of the Beach" with some illegal help. The laughter is canned for the sketch comedy show "You Can't Do That on Robot Chicken."