When Lynette's father-in-law pays a visit to to the family, she unwittingly learns a family secret. Meanwhile, Susan is disturbed by Julie's growing romance with Zach. Rex attempts to reconcile with Bree as she tries to play hard-to-get. Lastly, Gabrielle is shocked when John's parents ask her for a favor in convincing John to move back home as he officially turned eighteen and no longer wants to live at home and trying to pursue a relationship with Gabrielle.

It's Valentine's Day on Wisteria Lane, and love is all around (sort of), as Susan looks forward to a romantic date with Mike, until she learns a surprising fact about her favorite plumber. Meanwhile, after reconciling their relationship, Bree discovers something new about her husband Rex when it comes to his sexual needs. Lynette's neighbor accuses the Scavo twins of thievery as Lynette tries her best to handle the situation. Lastly, Gabrielle's work adventures continue as she gets a gig as a mattress model.

Mike and Susan face a crisis in their relationship when Susan tries to get Paul Young arrested by confessing to a police officer that he killed Mrs. Huber and Mike has her diaries as proof. The officer goes over to Mike to get the story, but Mike denies the whole thing. As Carlos continues serving his jail sentence, Gabrielle valiantly tries to free him. Bree goes to a romantic hotel with George, but requests they sleep in separate rooms.

Dr. Ron informs Susan that she needs a splenectomy. Gabrielle and her arch-enemy Sister Mary Bernard finally face off in church.

Also, Tom decides to apply for an empty position at Lynette's job, which leads to the arousal of past issues in their marriage. Lastly, Matthew and Danielle's relationship is found out by both their mothers, which leads to big repercussions later on for Bree and her past secret with Andrew last year.

Bree and Andrew finally reach an impasse in their relationship as tension has finally reached a critical point. Meanwhile, Ed finally fires Tom with the pressure from his wife. Lastly, Edie's private detective begins to uncover numerous details of Karl and Susan's relationship as of recently. Gabrielle is having a tough time keeping her servant in the country.

Lynette returns home from the hospital. Gabrielle decides to get back into modeling and travels to New York. Susan comes home to find Austin and Julie making out on her couch. Bree meets her antagonistic mother-in-law Gloria, with whom Orson is in a quarrel. Detective Ridley has Mike's house searched.

Bree isn't happy Alma has moved to Wisteria Lane. Gabrielle's secret admirer is revealed. The new Scavo Pizzeria faces an uncertain future. Julie and Austin go to Edie about giving them parental consent to buy birth control pills.

Susan meets her in-laws and finds out some family. Victor is still taking his chances with Gabrielle, while she has a devastating catastrophe at her home. Lynette is encountering new problems at the pizzeria while an unexpected relationship develops on Wisteria Lane.