Teenage orphan Joe Shimamura awakens on a surgical table with no memory of how he got there, but follows the advice of a strange voice in his head that helps him escape his island prison and robotic pursuers.

The 00 cyborgs are free, but fugitives from Black Ghost, the evil organization that created them.

The 00 cyborgs take shelter at the home of Dr. Koizumi, but soon realize they're not safe even there when Black Ghost sends the lightning-wielding 0010 to assassinate them.

During a rematch with the powerful 0010, the cyborgs realize they've got double the trouble to deal with.

Albert Heinrich, 004, recounts his tragic tale before going off into battle against a giant Black Ghost assassin.

While searching for the missing Dr. Koizumi, Joe, Great Britain and Albert come across an old mansion that turns out to be a haunted deathtrap.

The 00 cyborgs go to Joe's hometown, Tokyo, and come up against a gigantic invisible opponent.

The invisible menace is still on the loose, controlled by the mysterious 0013, a Black Ghost cyborg who's branched off on his own.

The 00 cyborgs race a Black Ghost submarine to the bottom of the sea over possession of a sunken electronic brain.

Black Ghost operatives at the South Pole kidnap a scientist's daughter to force him to finish a device that neutralizes all weapons.

003 gets some R&R in her hometown of Paris, but soon finds herself in a hallucinatory nightmare.

005, 006 and 007 become stranded on an isolated island with an abandoned Black Ghost munitions plant.

On a short return trip to London, 007 revisits memories of being a rags-to-riches stage actor prior to becoming a cyborg.

Black Ghost is stirring up a civil war in 008's home country, the Republic of Muamba, and using soulless Cyborg Men as minions.

008 discovers that the strongest Cyborg Man is his brainwashed best friend.

Skarle gets serious about recapturing the 00 cyborgs and has his subordinates try to sink the Dolphin.

While the cyborgs are on the loose in Black Ghost headquarters, 009 has a final confrontation with Skarle.

In a rare time of peace, Chang Changku opens his own Chinese restaurant, but is a nervous wreck when a famous food critic drops by.

Jet Link moves back to NYC, where he regales a little buddy about his exaggerated cyborg exploits while recalling what his life was really like pre-cyborg

Joe has a new pet dog that just might be responsible for a series of spontaneous combustion-like deaths.

Jet, Joe and G-Junior investigate the dinosaur sighting claims of a supposedly reformed Black Ghost scientist in the American Southwest.

The Mythos Arc opens with disasters all over the world and sightings of what seem to be the reincarnations of the Greek Gods of Mount Olympus.

The 00 cyborgs track the gods down to their island home in Greece, but 009 is defeated by the fiery Apollo.

The cyborgs discover the true nature of the reborn Greek gods shortly before Artemis is murdered, a crime 009 is blamed for.

The Greek gods make a last stand against the 00 cyborgs, while Dr. Gaia, a Black Ghost survivor, tries using their generator to destroy the world.

Dr. Gilmore takes a rare quiet afternoon to write in his journal and reflect about the 00 cyborgs, their enemies, and their future.

The 00 cyborgs get involved when fugitive children from a parallel world arrive on Earth with their powerful pursuers not far behind.

The cyborgs return with the children to their world, where 002 tries to motivate them to use their own psionic powers against the invasion force.

A powerful blue leopard-like beast attacks oil refineries and construction sites all over the world until it has a run-in with 005 in what used to be his village.

The team visits Computopia, a prototype city of the future run by a super-computer that becomes jealously murderous after getting a crush on 003.

Great Britain and Chang Changku happen across an island ruled by intelligent monsters that employ mindless zombies and giants.

Albert meets murderous doubles of himself in an old German castle.

009 wakes up from routine maintenance to discover that he's stuck in Acceleration Mode, so to him, everyone else is frozen.

Dr. Gilmore, 003 and 009 travel to Egypt, where they run afoul of a deadly virus that could be the curse of King Tut.

The 00 cyborgs investigate phantom sightings of El Dorado, the city of gold.

The team comes across a giant cobra in rural Japan that might be responsible for the area's extreme weather conditions.

In a small town in Japan, Joe encounters a little girl who claims to be a time traveler.

Dr. Gilmore thinks back on his own past, from first joining Black Ghost to the development of the cyborgs and his eventual betrayal of the organization.

When four people with psionic powers try to eliminate the team, the cyborgs suspect Black Ghost is back.

The four mutants, led by the obsessed Dr. Gamo Wisky, attempt to send the cyborgs into a post-apocalyptic future.

009 and his adversary, Rina, are trapped in a dystopic future in which Black Ghost still exists.

009 is reunited with his team in time to join their new allies against the psychotic, psionic mutant Kane and his sponsor, 001's father.

While investigating dinosaur-like creature attacks on the planet, Joe runs into old childhood friends who may not be so friendly anymore.

As the Yomi arc continues, the team reluctantly takes in a young woman with amnesia, while 008 has mixed feelings after Dr. Gilmore saves his life at the expense of becoming even less human.

With two telepathic sisters helping them, the 00 cyborgs discover the entrance to Yomi, the underground empire, but at the cost of the Dolphin.

In the underground empire, 009 is hypnotized and forced to attack his comrades, while Skarle is back after being presumed dead.

In the final episode of the Yomi arc, 009 fights Skarle and the true masters of Black Ghost aboard their giant statue in space.