British Museum curator Lady Alex Lindo-Parker jets off to the Amazon in search of Victorian explorer Percy Fawcett's lost camp. A series of mishaps sees her joined by maverick American adventurer Hooten and they stumble upon El Dorado.

Hooten asks Lady Alex to help him search for the Sibylline Books - a collection of lost mystical prophecies from ancient Rome. The British Museum curator accepts, but quickly finds herself scaling the Sistine Chapel, battling a sewer alligator and clashing with the Mafia.

Lady Alex and Hooten head to the remote Himalayan kingdom of Bhutan in search of an ancient scroll rumoured to have been written by the Buddha himself.

When Ella is kidnapped in Ethiopia, Lady Alex and Hooten head to Africa where they they must overcome crazed bandits and surly camels in order to save the day.

Lady Alex jets off to Moscow to help Hooten in his search for a lost Faberge egg and confronts her arch enemy from university, who now works for a shadowy black market collector, but they soon become entangled in a sinister criminal underworld.

Lady Alex and Hooten attempt to track down the priceless Cintamani jewel in Cambodia, but they quickly attract the attention of a ruthless drug gang.

Alex puts her wedding in jeopardy as she follows Hooten to an idyllic Caribbean island, searching for Captain Henry Morgan's buried pirate treasure. With half a map each and other hunters on their tail, this larger-than-life expedition threatens to derail the biggest day in Lady Alex's life.