Former international CIA operative, Wesley Cole returns home and assumes duty as a police officer with the LAPD. Cole will find himself navigating a new partnership with Murtaugh, as he adjusts to life in Los Angeles. Avery continues his campaign for city council.

New partners Murtaugh and Cole attempt to find a steady rhythm as they work to solve the murder of a finance executive. Cole navigates his role with his ex- and his daughter. Avery grapples with the outcome of his campaign for city council.

Murtaugh and Cole investigate a robbery of a truck filled with fine art. Cole deals with lingering feelings for Natalie following a new development in her life. Riana blackmails Murtaugh into letting her go to a concert after she catches him in a lie that he told Trish.

Murtaugh turns to Cole's former mentor for help on a high-stakes cartel case. Murtaugh and Trish meet Natalie and Maya for the first time. Tensions mount between Bailey and 'The Gute' as the new partners begin to work together.

Cole wants to talk to Natalie about their relationship before it's too late, but a wrench is thrown in his plans after he bumps into a new ADA, Erica. After being kicked out of the house for Trish's girl's night, Murtaugh finds himself an unlikely friend.

Cole finds himself on the rebound after Natalie's engagement, and his new romantic interest, Julie, has an unexpected connection to A.D.A. Erica, complicating things at work. Meanwhile, Murtaugh worries about the connection between the murder he's investigating and a new opportunity for Trish to serve as co-counsel on a high-profile lawsuit with Leo Getz.