Teresa brokers a deal with an eccentric smuggler, Camila struggles to rebuild her empire, and Epifanio takes on a new partner he may not be able to control.

While trying to destroy Epifanio's drug smuggling tunnels, Teresa and James come face-to-face with a group of American border vigilantes.

Teresa's loyalties are tested when she is asked to assassinate a DEA mole.

Teresa, James and Guero travel to Bolivia in search of a new supplier: the mysterious and dangerous narco-cult leader El Santo.

Captured by narco-cult leader El Santo, Teresa embarks on a spiritual journey with real-world consequences.

With their payment deadline looming, Teresa and Camila need to find a new distributor, but their plans become threatened.

Camila sends Teresa and her crew to Chicago to secure a meeting with an elusive drug distributor.

An uncharacteristic blunder forces Camila and Teresa to go on the run from hit men, but as they flee, their bond grows deeper.

When Teresa competes with James for Camila's trust, she begins to question everything; Epifanio plans to leave the cartel world for good.

Teresa goes on the run to flee Camila, but she realizes the time for running is over after a showdown with hired guns.

Eager to break away from Camila, Teresa forges new, uneasy alliances and brings the fight to Camila's doorstep.

In the final showdown between Teresa and Camila, they are forced to accept the truth that there can be only one queen.