Säsong 1 av Van Helsing hade premiär den 23 september 2016.

Efter tre år i koma vaknar Vanessa upp. Världen är nu full av vampyrer och hon och en udda skara andra överlevare måste kämpa för att hålla sig vid liv.

Säsong 2 av Van Helsing hade premiär den 5 oktober 2017.

Season two of Van Helsing pushes Vanessa and the other Survivors further into the world of the vampire apocalypse, where they discover old alliances have crumbled and new connections expose long-buried secrets about the Rising, the Van Helsing heritage, and the survival of humankind itself.

Säsong 3 av Van Helsing hade premiär den 5 oktober 2018.

The first of four vampire Elders has been freed (although it proves itself to be loyal to the Van Helsing clan) and legend has it that when their four Totems are combined the Dark One will be resurrected. Now it's a race against time as Vanessa and her ragtag group of heroes faces off against the forces of darkness.

Säsong 4 av Van Helsing hade premiär den 27 september 2019.

Sam has fulfilled his destiny to become the 4th Elder & now our post-apocalyptic world is even closer to seeing the Dark One resurrected. Vanessa vows to follow the light & fight the darkness that has taken everything she loves. Just when she thought she was alone in her mission she meets two young women, Violet and Jack-who have unique and mysterious vampire fighting abilities all their own.

Säsong 5 av Van Helsing hade premiär den 16 april 2021.

Vanessa, Violet, and Jack will risk it all to finally bring an end to the Dark One once and for all. The Van Helsings must figure out ways to escape and evade the various obstacles in their path to prevent them from their mission, leading to an epic final showdown between the Van Helsings and the Dark One. Who will win the battle between light and dark?