Dr. Watters befriends a 12-year-old girl when she's admitted with an apparently self-inflected wound to her transplanted kidney. Austin has another rough day, with the shakes during a surgery and a message from her ex-husband that he might be moving to Boston and taking their daughter with him. Diane finds out about Billy's previous relationship with Kate.

Aaron faces a huge moral dilemma when he's asked to operate on a death-row inmate scheduled to be executed in two weeks. McNeil treats a feisty old lady whose daughter is an old flame os his. Dr. Watters entertains an amnesiac, believing that he's a distinguished visiting doctor.

A doctor with Tourette's Syndrome is brought to Chicago Hope to operate on an infant with a severe heart defect. A patient comes into the ER with, what he claims to be, Albert Einstein's brain and gives it to Dr. Wilkes. A woman is using plastic surgery to make herself look like a Barbie Doll.

Shutt and Simon invent a procedure and use it to save the life of a girl. McNeil treat a wrestler who's been using steroids.